772828
5-Norbornene-2-endo-acetic acid
Synonym(s):
Bicyclo[2.2.1]hept-5-en-2-ylacetic acid, Norbornene acetic acid
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form
liquid
Quality Segment
reaction suitability
reaction type: click chemistry, reagent type: linker
refractive index
n
density
1.124 g/mL at 25 °C
functional group
carboxylic acid
SMILES string
OC(CC1C[C@@H]2C=C[C@H]1C2)=O
InChI
1S/C9H12O2/c10-9(11)5-8-4-6-1-2-7(8)3-6/h1-2,6-8H,3-5H2,(H,10,11)/t6-,7+,8?/m1/s1
InChI key
HRVGJQMCNYJEHM-KVARREAHSA-N
Application
Carboxylic acid functionalized norbornene. Carboxylic acid can be used to modify amine containing compounds such as lysine residues on proteins/peptides via standard peptide coupling methods. Norbornene has been shown to react with 1,2,4,5-tetrazines in an inverse electron demand Diels-Alder cycloaddition reaction, which is a bioorthogonal click chemistry reaction demonstrated to be useful in biological imaging applications.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 3
Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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