790249
Poly(D,L-lactide-co-glycolide)-block-poly(ethylene glycol)-block-poly(D,L-lactide-co-glycolide) based poly(ether ester urethane)
average Mn (6,000-15,000)
Synonym(s):
PEEU, PLGA-PEG-PLGA urethane, VISCOPRENE® 9, poly(ester ether urethane)
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About This Item
Linear Formula:
[C2H2N2O2R[(C3H4O2)x(C2H2O2)y]m[C2H4O]lO[(C3H4O2)x(C2H2O2)y]m]n
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.23
form
amorphous solid
feed ratio
13:(70:17) (PEG:(D,L-lactide:glycolide)), lactide:glycolide 80:20
mol wt
PEG average Mn 400, average Mn (6,000-15,000)
degradation timeframe
<4 months
transition temp
Tg <0 °C
PDI
<2.0
storage temp.
2-8°C
SMILES string
CC(N[R]NC(OC(C)C(OCC(OCCOC(C(C)OC(COC)=O)=O)=O)=O)=O)=O.CC(N[R]NC(OCCCOC)=O)=O
Application
This poly(ether ester urethane) based on PLGA-PEG-PLGA triblock copolymers linked with a diisocyanate is a biodegradable, resorbable gel former for use in drug delivery systems. This polymer doesn′t rely on temperature or pH to induce gelation, and therefore forms more consistent and faster-setting drug delivery depots. Through combination of various gel formers and/or diluents, drug release profiles may be modulated to exhibit fast burst release through extended (up to 1 month) zero-order release profile. Mass loss of the resultant drug delivery depots is complete within 4 months.
Legal Information
Product of Poly-Med, Inc. VISCOPRENE® is a registered trademark of Poly-Med, Inc.
Viscoprene is a registered trademark of Poly-Med, Inc.
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Storage Class
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| 790249-1G | 04061826647196 |
| 790249-5G | 04061833332719 |