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Merck
CN

791369

Tang-Yu Auxiliary

97%

Synonym(s):

2-(2-Cyanophenoxy)-2-fluoroacetic acid

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About This Item

Empirical Formula (Hill Notation):
C9H6FNO3
CAS Number:
Molecular Weight:
195.15
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352002
MDL number:
Assay:
97%
Form:
solid
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InChI

1S/C9H6FNO3/c10-8(9(12)13)14-7-4-2-1-3-6(7)5-11/h1-4,8H,(H,12,13)

SMILES string

O=C(O)C(F)OC1=C(C#N)C=CC=C1

InChI key

WPPDDNKKUDYVMF-UHFFFAOYSA-N

assay

97%

form

solid

reaction suitability

reaction type: C-C Bond Formation, reagent type: catalyst, reagent type: ligand
reaction type: C-H Activation

mp

105-108 °C

functional group

carboxylic acid, fluoro, nitrile

Quality Level

Application

The Tang-Yu Auxiliary is a recyclable template for highly meta-selective C-H activation of N-methylanilines as reported by Yu and coworkers.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Yu program focuses on efficient C–H bond activation for drug synthesis, using simple starting materials.

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