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About This Item
Empirical Formula (Hill Notation):
C11H24N2O2
CAS Number:
Molecular Weight:
216.32
Beilstein:
2219107
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22
Quality Level
Assay
≥98.0% (NT)
form
liquid
reaction suitability
reagent type: cross-linking reagent
refractive index
n20/D 1.462
density
0.965 g/mL at 20 °C (lit.)
functional group
Boc
amine
SMILES string
NCCCCCCNC(OC(C)(C)C)=O
InChI
1S/C11H24N2O2/c1-11(2,3)15-10(14)13-9-7-5-4-6-8-12/h4-9,12H2,1-3H3,(H,13,14)
InChI key
RVZPDKXEHIRFPM-UHFFFAOYSA-N
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Application
N-Boc-1,6-hexanediamine can be used as a linear hexyl spacer (C6-spacer) to synthesize:
- Biodegradable poly(disulfide amine)s for gene delivery.
- A multifunctional dendrimer for theranostics.
- Polyamide platinum anti-cancer complexes designed to target cancer specific DNA sequences.
- Self-assembled monolayers (SAMs) that resist adsorption of proteins.
- [N-(6-(4-Hydroxy-6-isopropylamino-1,3,5-triazin-2-ylamino)hexyl)-5-hydroxy-1,4-naphthoquinone-3-propionamide] (JUG-HATZ), which can be used in designing electrochemical immunosensors.
Reagent for the introduction of a C6-spacer.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 3
Flash Point(F)
257.0 °F - closed cup
Flash Point(C)
125 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Duffey TA, et al.
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Polyamide platinum anticancer complexes designed to target specific DNA sequences.
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Inorganic Chemistry, 45(15), 6004-6013 (2006)
Preparation of mixed self-assembled monolayers (SAMs) that resist adsorption of proteins using the reaction of amines with a SAM that presents interchain carboxylic anhydride groups.
Chapman R G, et al.
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To avoid poly(ethylene glycol)-related issues of nanomedicines such as accelerated blood clearance, fully N-2-hydroxypropyl methacrylamide (HPMAm)-based polymeric micelles decorated with biotin for drug delivery were designed. To this end, a biotin-functionalized chain transfer agent (CTA), 4-cyano-4-[(dodecylsulfanylthiocarbonyl)-sulfanyl]pentanoic acid (biotin-CDTPA), was synthesized
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