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Merck
CN

79229

N-Boc-1,6-hexanediamine

≥98.0% (NT)

Synonym(s):

N-Boc-1,6-diaminohexane, tert-Butyl-N-(6-aminohexyl)carbamate

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About This Item

Empirical Formula (Hill Notation):
C11H24N2O2
CAS Number:
Molecular Weight:
216.32
UNSPSC Code:
12352116
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2219107
Assay:
≥98.0% (NT)
Form:
liquid
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Quality Level

assay

≥98.0% (NT)

form

liquid

reaction suitability

reagent type: cross-linking reagent

refractive index

n20/D 1.462

density

0.965 g/mL at 20 °C (lit.)

functional group

Boc, amine

SMILES string

NCCCCCCNC(OC(C)(C)C)=O

InChI

1S/C11H24N2O2/c1-11(2,3)15-10(14)13-9-7-5-4-6-8-12/h4-9,12H2,1-3H3,(H,13,14)

InChI key

RVZPDKXEHIRFPM-UHFFFAOYSA-N

Application

N-Boc-1,6-hexanediamine can be used as a linear hexyl spacer (C6-spacer) to synthesize:
  • Biodegradable poly(disulfide amine)s for gene delivery.
  • A multifunctional dendrimer for theranostics.
  • Polyamide platinum anti-cancer complexes designed to target cancer specific DNA sequences.
  • Self-assembled monolayers (SAMs) that resist adsorption of proteins.
  • [N-(6-(4-Hydroxy-6-isopropylamino-1,3,5-triazin-2-ylamino)hexyl)-5-hydroxy-1,4-naphthoquinone-3-propionamide] (JUG-HATZ), which can be used in designing electrochemical immunosensors.
Reagent for the introduction of a C6-spacer.


pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

257.0 °F - closed cup

flash_point_c

125 °C - closed cup

ppe

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter



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Design and synthesis of substrates for newborn screening of Maroteaux?Lamy and Morquio A syndromes.
Duffey TA, et al.
Bioorganic & Medicinal Chemistry, 20(20), 5994-5996 (2010)
Synthesis, penetrability and intracellular targeting of fluorescein-tagged peptoids and peptide?peptoid hybrids
Unciti-Broceta A, et al.
Bioorganic & Medicinal Chemistry, 17(3), 959-966 (2009)
Preparation of mixed self-assembled monolayers (SAMs) that resist adsorption of proteins using the reaction of amines with a SAM that presents interchain carboxylic anhydride groups.
Chapman R G, et al.
Langmuir, 16(17), 6927-6936 (2000)



Global Trade Item Number

SKUGTIN
79229-1G04061832950761
79229-5G04061838076472