79229
N-Boc-1,6-hexanediamine
≥98.0% (NT)
Synonym(s):
N-Boc-1,6-diaminohexane, tert-Butyl-N-(6-aminohexyl)carbamate
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About This Item
Empirical Formula (Hill Notation):
C11H24N2O2
CAS Number:
Molecular Weight:
216.32
UNSPSC Code:
12352116
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
2219107
Assay:
≥98.0% (NT)
Form:
liquid
Quality Level
assay
≥98.0% (NT)
form
liquid
reaction suitability
reagent type: cross-linking reagent
refractive index
n20/D 1.462
density
0.965 g/mL at 20 °C (lit.)
functional group
Boc, amine
SMILES string
NCCCCCCNC(OC(C)(C)C)=O
InChI
1S/C11H24N2O2/c1-11(2,3)15-10(14)13-9-7-5-4-6-8-12/h4-9,12H2,1-3H3,(H,13,14)
InChI key
RVZPDKXEHIRFPM-UHFFFAOYSA-N
Application
N-Boc-1,6-hexanediamine can be used as a linear hexyl spacer (C6-spacer) to synthesize:
- Biodegradable poly(disulfide amine)s for gene delivery.
- A multifunctional dendrimer for theranostics.
- Polyamide platinum anti-cancer complexes designed to target cancer specific DNA sequences.
- Self-assembled monolayers (SAMs) that resist adsorption of proteins.
- [N-(6-(4-Hydroxy-6-isopropylamino-1,3,5-triazin-2-ylamino)hexyl)-5-hydroxy-1,4-naphthoquinone-3-propionamide] (JUG-HATZ), which can be used in designing electrochemical immunosensors.
Reagent for the introduction of a C6-spacer.
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 3
flash_point_f
257.0 °F - closed cup
flash_point_c
125 °C - closed cup
ppe
Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter
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Preparation of mixed self-assembled monolayers (SAMs) that resist adsorption of proteins using the reaction of amines with a SAM that presents interchain carboxylic anhydride groups.
Chapman R G, et al.
Langmuir, 16(17), 6927-6936 (2000)
Construction of a well-defined multifunctional dendrimer for theranostics.
Ornelas C, et al.
Organic Letters, 13(5), 976-979 (2011)
Yan Wang et al.
Journal of controlled release : official journal of the Controlled Release Society, 328, 970-984 (2020-09-15)
To avoid poly(ethylene glycol)-related issues of nanomedicines such as accelerated blood clearance, fully N-2-hydroxypropyl methacrylamide (HPMAm)-based polymeric micelles decorated with biotin for drug delivery were designed. To this end, a biotin-functionalized chain transfer agent (CTA), 4-cyano-4-[(dodecylsulfanylthiocarbonyl)-sulfanyl]pentanoic acid (biotin-CDTPA), was synthesized
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 79229-1G | 04061832950761 |
| 79229-5G | 04061838076472 |