Skip to Content
Merck
CN

Key Documents

View All Documentation

793841

2,2-Difluoroacetophenone

Synonym(s):

α,α-Difluoroacetophenone, 2,2-Difluoro-1-phenylethanone, Difluoromethyl phenyl ketone

Sign In to View Organizational & Contract Pricing.

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):
C8H6F2O
CAS Number:
395-01-7
Molecular Weight:
156.13
NACRES:
NA.22
PubChem Substance ID:
329768421
UNSPSC Code:
12352101
MDL number:
MFCD06246879
Form:
liquid
Technical Service
Need help? Our team of experienced scientists is here for you.
Let Us Assist

form

liquid

Quality Segment

reaction suitability

reaction type: Halogenations

density

1.180±0.06 g/mL

functional group

fluoro, ketone, phenyl

SMILES string

FC(F)C(C1=CC=CC=C1)=O

InChI

1S/C8H6F2O/c9-8(10)7(11)6-4-2-1-3-5-6/h1-5,8H

InChI key

OLYKCPDTXVZOQF-UHFFFAOYSA-N

Application

Product was reported by Hartwig and coworkers in the one-pot synthesis of difluoromethylated arenes from aryl chlorides and bromides.


Pd-Catalyzed a-Arylation of a;a-Difluoroketones with Aryl Bromides and Chlorides. A Route to Difluoromethylarenes

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Codes

H315,H319

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

WGK

WGK 3

Flash Point (°F)

158.0 °F

Flash Point (°C)

70 °C

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library