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79625

N,N-Dimethylphosphoramic dichloride

≥98.0% (AT)

Synonym(s):

DMPADC, Dimethylamidophosphoric dichloride

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About This Item

Linear Formula:
(CH3)2NP(O)Cl2
CAS Number:
Molecular Weight:
161.95
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
211-641-2
Beilstein/REAXYS Number:
969956
MDL number:
Assay:
≥98.0% (AT)
Form:
liquid
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Quality Segment

assay

≥98.0% (AT)

form

liquid

refractive index

n20/D 1.464

bp

77-79 °C/11 mmHg (lit.)

density

1.362 g/mL at 20 °C (lit.)

functional group

phosphoramide

storage temp.

2-8°C

SMILES string

CN(C)P(Cl)(Cl)=O

InChI

1S/C2H6Cl2NOP/c1-5(2)7(3,4)6/h1-2H3

InChI key

YNHXBEVSSILHPI-UHFFFAOYSA-N

Application

N,N-Dimethylphosphoramic dichloride can be used as a reagent:
  • For the activation of carboxylic acids.
  • To prepare functionalized β-lactams by reacting with acetic acids and imines.
  • To synthesize phosphoramidic esters by reacting with alcohols in the presence of a base catalyst.
  • To prepare [1,2,4]triazolo[4,3-c][1,3,5,2]triazaphosphinine-5-oxide derivatives by reacting with N-alkyl/aryl-N′-(4H-1,2,4-triazol-3-yl) amidines in the presence of triethylamine.



Pictograms

Corrosion

Signal Word

Danger

Hazard Codes

Hazard Classifications

Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

PPE (personal protective equipment)

Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter



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