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Sigma-Aldrich

5-Hydroxy-DL-tryptophan

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Synonym(s):
DL-2-Amino-3-(5-hydroxyindolyl)propionic acid, DL-5-HTP
Empirical Formula (Hill Notation):
C11H12N2O3
CAS Number:
56-69-9
Molecular Weight:
220.22
Beilstein:
88199
EC Number:
200-284-8
MDL number:
MFCD00005651
PubChem Substance ID:
329768568

form

solid

mp

298-300 °C (dec.) (lit.)

SMILES string

NC(Cc1c[nH]c2ccc(O)cc12)C(O)=O

InChI

1S/C11H12N2O3/c12-9(11(15)16)3-6-5-13-10-2-1-7(14)4-8(6)10/h1-2,4-5,9,13-14H,3,12H2,(H,15,16)

InChI key

LDCYZAJDBXYCGN-UHFFFAOYSA-N

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Biochem/physiol Actions

Immediate precursor of serotonin; L-aromatic amino acid decarboxylase substrate.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Infiltration of activated immune cells and increased cytokine production define the immunophenotype of gastrointestinal (GI) inflammation. In addition, intestinal inflammation is accompanied by alteration in the numbers of serotonin (5-hydroxytryptamine; 5-HT) synthesizing enterochromaffin (EC) cells and in 5-HT amount. It
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