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799041

Poly(ethylene glycol) methyl ether-block-poly(L-lactide-co-glycolide)

PEG average Mn 5,000, PLGA average Mn 25,000, lactide:glycolide 50:50

Synonym(s):

PEG-PLGA, PEG-b-PLGA

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About This Item

Linear Formula:
CH3[C2H4O]nO[(C2H2O2)x(C3H4O2)y]mH
NACRES:
NA.23
UNSPSC Code:
12162002
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form

powder

Quality Segment

mol wt

PEG average Mn 5,000, PLGA average Mn 25,000

composition

lactide:glycolide 50:50

storage temp.

2-8°C

Application

Amphiphilic block copolymers (AmBC) are made up of two chemically different homopolymer blocks. One of the block is hydrophilic and the other one is hydrophobic. These macromolecules have the properties to self-assemble when dissolved in an aqueous media. PEG-PLGA is one the most commonly used biodegradable amphiphilic block copolymers for drug delivery applications. PEG is the hydrophilic part and PLGA is the hydrophobic part.Used in the synthesis of targeted nanoparticles which are used for differential delivery and controlled release of drugs

Features and Benefits

  • Good biocompatibility, low immunogenicity and good degradability.
  • Properties can be easily modulated by changing the block copolymer segment sizes to suit a particular application.

Storage Class

11 - Combustible Solids

WGK

WGK 3

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