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Merck
CN

804150

SnAP 2,3-Bicyclo-(3,4-Pyr) M Reagent

Synonym(s):

(3R,4R)-tert-butyl 3-amino-4-((tributylstannyl)methoxy) pyrrolidine-1-carboxylate

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About This Item

Empirical Formula (Hill Notation):
C22H46N2O3Sn
Molecular Weight:
505.32
MDL number:
UNSPSC Code:
12352103
PubChem Substance ID:
NACRES:
NA.22
Form:
liquid
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SMILES string

CCCC[Sn](CCCC)(CO[C@H]1CN(C(OC(C)(C)C)=O)C[C@@H]1N)CCCC

InChI

1S/C10H19N2O3.3C4H9.Sn/c1-10(2,3)15-9(13)12-5-7(11)8(6-12)14-4;3*1-3-4-2;/h7-8H,4-6,11H2,1-3H3;3*1,3-4H2,2H3;/t7-,8-;;;;/m0..../s1

InChI key

URTKNAYUDTUPJM-CFACWHMASA-N

form

liquid

density

1.180 at 25 °C

functional group

ether

storage temp.

−20°C

Quality Level

Application

SnAP Reagents provide a one-step route, in tandem with various aldehyde substrates, to saturated N-heterocycles. The synthesis of N-heterocycles through SnAP Reagents requires mild reaction conditions, and aldehydes bearing aryl, heteroaryl, glyoxyl, aliphatic, and halogenated groups are well tolerated. This product was introduced in collaboration with the Bode Research Group

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signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Acute Tox. 4 Dermal - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT RE 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Protocols

SnAP Reagents facilitate synthesis of saturated N-heterocycles for diverse structures.

SnAP试剂是一种种类不断扩充的试剂,现在可用来方便地合成中等环(6-9元)饱和N-杂环,包括双环和螺环结构。

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