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Merck
CN

84570

Sarcosine methyl ester hydrochloride

≥97.0% (T)

Synonym(s):

N-Methylglycine methyl ester hydrochloride

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About This Item

Linear Formula:
CH3NHCH2COOCH3 · HCl
CAS Number:
Molecular Weight:
139.58
UNSPSC Code:
12352108
NACRES:
NA.22
PubChem Substance ID:
EC Number:
236-853-2
Beilstein/REAXYS Number:
3619268
MDL number:
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Quality Level

assay

≥97.0% (T)

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

impurities

≤3% sarcosine hydrochloride

application(s)

peptide synthesis

SMILES string

Cl.CNCC(=O)OC

InChI

1S/C4H9NO2.ClH/c1-5-3-4(6)7-2;/h5H,3H2,1-2H3;1H

InChI key

HQZMRJBVCVYVQA-UHFFFAOYSA-N



Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

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D O H Teare et al.
The journal of physical chemistry. B, 109(44), 20923-20928 (2006-07-21)
A new class of protein-resistant film based on N-substituted glycine derivatives is described. Pulsed plasma deposited poly(N-acryloylsarcosine methyl ester) coatings are shown to be resistant toward the adsorption of fibrinogen and lysozyme. Deposition and UV irradiation of the polymer through
C Alarcon et al.
Bioscience reports, 5(7), 581-587 (1985-07-01)
Glycine methyl ester, an inhibitor of transglutaminase, decreased glucose-stimulated insulin release and delayed proinsulin conversion in rat pancreatic islets pulse-labelled with L-[4-3H]phenylalanine. Sarcosine methyl ester, which does not inhibit transglutaminase activity, failed to affect insulin release and proinsulin conversion. The
M A Lindsay et al.
Bioscience reports, 10(6), 557-561 (1990-12-01)
Ca(2+)-Induced insulin release from electropermeabilised islets is inhibited by the transglutaminase inhibitors monodansylcadaverine, glycine methylester, methylamine and cystamine but not by the control compounds dimethyl monodansylcadaverine and sarcosine methylester which lack the primary amine group. Neither monodansylcadaverine nor glycine methylester



Global Trade Item Number

SKUGTIN
84570-250G04061833007952
84570-50G04061832643021