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Sigma-Aldrich

Polyvinylpyrrolidone

powder, average Mw ~55,000

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Synonym(s):
PVP, Polyvidone, Povidone
Linear Formula:
(C6H9NO)n
CAS Number:
9003-39-8
MDL number:
MFCD00149016
PubChem Substance ID:
24888426
NACRES:
NA.23

form

powder

Quality Level

200

mol wt

average Mw ~55,000

SMILES string

C=CN1CCCC1=O

InChI

1S/C6H9NO/c1-2-7-5-3-4-6(7)8/h2H,1,3-5H2

InChI key

WHNWPMSKXPGLAX-UHFFFAOYSA-N

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General description

PVP has biocompatibility, low toxicity, adhesive characteristics, complexing stability, relatively inert behavior, and is resistant to thermal degradation. It is readily prepared by the polymerization of N-vinyl-2-pyrrolidone or by Reppe synthesis technique.

Application

PVP is one of the constituents used in the synthesis and coating of silver nanocubes. It serves as a reducing agent and colloidal stabilizer in the synthesis of palladium nanobars, triangular,nanoplates,twinned nanorods and bipyramids. It is also used as a capping agent in the synthesis of silver nanospheres,gold nanoframes. General applications of PVP are: in pharmaceutical, food, beverage, cosmetic, toiletry and photographic industries.

Other Notes

Polyvinylpyrrolidone is a component of Denhardt′s Solution and is included at a concentration of 1% (w/v) in the standard 50X stock solution.

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Rapid synthesis of small silver nanocubes by mediating polyol reduction with a trace amount of sodium sulfide or sodium hydrosulfide.
Siekkinen AR, et al.
Chemical Physics Letters, 432(4-6), 491- 496 null
Robinson BV, et al. et al.
PVP: A critical review of the kinetics and toxicology of polyvinlypyrrolidone (Povidone) (1990)
Gold nanocages for cancer imaging and therapy
Au L, et al.
Cancer Nanotechnology, 83-99 (2010)
Synthesis and characterization of fivefold twinned nanorods and right
bipyramids of palladium
Xiong Y, et al.
Chemical Physics Letters, 440, 273-278 (2007)
Mario Battisti et al.
Frontiers in bioengineering and biotechnology, 7, 296-296 (2019-11-30)
Transdermal drug delivery represents an appealing alternative to conventional drug administration systems. In fact, due to their high patient compliance, the development of dissolvable and biodegradable polymer microneedles has recently attracted great attention. Although stamp-based procedures guarantee high tip resolution
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