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86578

Sigma-Aldrich

Tetraethyl orthosilicate

≥99.0% (GC)

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Synonym(s):
Orthosilicic acid tetraethyl ester, Silicon tetraethoxide, TEOS, Tetraethoxysilane, Tetraethoxysilicon(IV), Tetraethyl silicate
Linear Formula:
Si(OC2H5)4
CAS Number:
Molecular Weight:
208.33
Beilstein:
1422225
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.22

vapor density

7.2 (vs air)

Quality Level

vapor pressure

<1 mmHg ( 20 °C)

Assay

≥99.0% (GC)

form

liquid

refractive index

n20/D 1.382 (lit.)
n20/D 1.383

bp

168 °C (lit.)

density

0.933 g/mL at 20 °C (lit.)

SMILES string

CCO[Si](OCC)(OCC)OCC

InChI

1S/C8H20O4Si/c1-5-9-13(10-6-2,11-7-3)12-8-4/h5-8H2,1-4H3

InChI key

BOTDANWDWHJENH-UHFFFAOYSA-N

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General description

Tetraethyl orthosilicate (TEOS) is an inorganic material that can be used as a silica source for the synthesis of silica-based materials such as silicon dioxide, silicon oxycarbides, silanol, siloxane polymer, and organosilicon thin films for a variety of applications. It can also be used in the synthesis of blended membranes, and the production of aerogel. Other applications include coatings for carpets and other objects.

Application

Tetraethyl orthosilicate (TEOS) can be used:
  • As a reagent along with ferric chloride in the synthesis of dihydropyrimidinones.
  • As a modifier in fabrication of humidity sensing material, poly(2-acrylamido-2-methylpropane sulfonate) (poly-AMPS).
  • As a medium to synthesize triarylamines and diaryl ethers via copper catalyzed, ligand free-Ullmann reaction.
  • As a precursor for the preparation of silica xerogel which finds application in pharmaceutical drug carriers.
  • As a precursor for the synthesis of spherical silica particles by Stober process.

Commonly used as a precursor to prepare xerogel
Will interact with dodecylamine in the formation of intercalation compounds of H+-magadiite and used in a study of mixed-metal bioactive glasses.

Pictograms

FlameExclamation mark

Signal Word

Warning

Hazard Statements

Hazard Classifications

Acute Tox. 4 Inhalation - Eye Irrit. 2 - Flam. Liq. 3 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

113.0 °F - closed cup

Flash Point(C)

45 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

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  1. How does the storage temperature relate to shipping conditions?

    The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment. See Shipping and Storage for more information.

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  5. What is the Department of Transportation shipping information for this product?

    Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product. 

  6. What type of applications can Product No. 86578, Tetraethyl orthosilicate (TEOS), be used in?

    TEOS can be used to synthesize sol-gels or aerogels.

  7. How do you create a sol-gel with Tetraethyl orthosilicate (TEOS), Product No. 86578?

    TEOS can be polymerized with water; the polymerization is based on the hydrolysis or the Si-O-Et groups through forming networks linked by Si-O-Si groups.

  8. How can I accelerate the polymerization of Tetraethyl orthosilicate (TEOS), Product No. 86578?

    The polymerization of TEOS can be accelerated or driven to completion by the addtion of acid or base, both of which serve as a catalyst.

  9. What are the applications of sol-gels formed from Tetraethyl orthosilicate (TEOS), Product No. 86578?

    One of the most improtant application of the sol-gel process is the snythesis of zeolites. Other applications are optical ceramic materials or functionalized biosensors.

  10. What is the vapor pressure of Tetraethyl orthosilicate (TEOS), Product No. 86578, at room temperature?

    The vapor pressure of TEOS at room temperature is 1.5 Torr.

  11. My question is not addressed here, how can I contact Technical Service for assistance?

    Ask a Scientist here.

Silica xerogels as pharmaceutical drug carriers
Quintanar-Guerrero D, et al.
Expert Opinion on Drug Delivery, 5(6), 485-498 (2009)
Ullmann reaction in tetraethyl orthosilicate: a novel synthesis of triarylamines and diaryl ethers
Zhao Y, et al.
Chemical Communications (Cambridge, England), 30(449), 3186-3188 (2007)
Modification of synthetic carpet using chitosan-titania nanocomposite for self-cleaning purposes
Sulaeman MI, et al.
AIP Conference Proceedings, 2175(1), 020077-020077 (2019)
The Organosilicon thin Film Deposited Using an Atmospheric Pressure Dual-Frequency 50 kHz/33 MHz Frequency MicroPlasma Jet
Yuan QH, et al.
Contributions to Plasma Physics, 56(9), 870-877 (2016)
A spectroscopic study of an anhydrous tetraethyl orthosilicate-boric acid-ethanol system
Zha Congji, et al.
Journal of Sol-Gel Science and Technology, 13(1-3), 103-107 (1998)

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