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900572

Biotinylated isoxazole

95%

Synonym(s):

6-(5-(Thiophen-2-yl)isoxazole-3-carboxamido)hexyl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate, B-Isox, B-isox

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About This Item

Empirical Formula (Hill Notation):
C24H32N4O5S2
CAS Number:
1377605-22-5
Molecular Weight:
520.66
UNSPSC Code:
12352108
NACRES:
NA.22
MDL number:
MFCD26405989
Assay:
95%
Form:
powder or crystals
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Quality Segment

100

assay

95%

form

powder or crystals

SMILES string

[s]1c(ccc1)c2[o]nc(c2)C(=O)NCCCCCCOC(=O)CCCC[C@@H]3SC[C@@H]4NC(=O)N[C@@H]43

InChI key

KZZXSHXZDYGEDW-XJABCFGWSA-N

Application

When exposed to cells or tissue lysates, biotinylated isoxazole (b-isox) was shown to precipitate RNA-binding proteins with significant overlap to the components of RNA granules. By reversibly aggregating and disaggregating structures similar to RNA granules, b-isox has lent insight to polypeptides necessary for the reversible aggregation of RNA-binding proteins.

This product was previously listed as T511617.

Other Notes

Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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