900602
4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid
≥95%
Synonym(s):
Carboxyl benzophenone alkyne, Probe building block
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About This Item
Empirical Formula (Hill Notation):
C17H12O4
CAS Number:
Molecular Weight:
280.27
UNSPSC Code:
12352106
NACRES:
NA.22
MDL number:
Assay:
≥95%
Form:
solid
Quality Segment
assay
≥95%
form
solid
reaction suitability
reaction type: click chemistry, reagent type: cross-linking reagent
functional group
alkyne, carboxylic acid
storage temp.
−20°C
SMILES string
O=C(C1=CC=C(OCC#C)C=C1)C2=CC=C(C(O)=O)C=C2
InChI
1S/C17H12O4/c1-2-11-21-15-9-7-13(8-10-15)16(18)12-3-5-14(6-4-12)17(19)20/h1,3-10H,11H2,(H,19,20)
InChI key
URDMKFAPEKSQDV-UHFFFAOYSA-N
Application
4-(4-(Prop-2-yn-1-yloxy)benzoyl)benzoic acid is used for chemical probe synthesis, this trifunctional building block contains a light-activated benzophenone, alkyne tag, and carboxylic acid synthetic handle. When appended to a ligand or pharmacophore through its acid linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
Other Notes
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Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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