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900618

3-(3-(Bromomethyl)-5-ethynylphenyl)-3-(trifluoromethyl)-3H-diazirine

Name: 3-(3-(Bromomethyl)-5-ethynylphenyl)-3-(trifluoromethyl)-3<I>H</I>-diazirine
Brand: ALDRICH

95%

Synonym(s):

Bromo diazirine alkyne, Probe building block

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About This Item

Empirical Formula (Hill Notation):

C₁₁H₆BrF₃N₂

CAS Number:

849607-28-9

Molecular Weight:

303.08

NACRES:

NA.22

UNSPSC Code:

12352200

Assay:

95%

Form:

solid

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Properties

assay

95%

form

solid

availability

available only in USA

storage temp.

−20°C

Description

Application

3-(3-(Bromomethyl)-5-ethynylphenyl)-3-(trifluoromethyl)-3H-diazirine is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and bromine synthetic handle. When appended to a ligand or pharmacophore through its brominated linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Other Notes

Technology Spotlight: Trifunctional Probe Building Blocks
Design of dantrolene-derived probes for radioisotope-free photoaffinity labeling of proteins involved in the physiological Ca²⁺ release from sarcoplasmic reticulum of skeletal muscle

pictograms

GHS02

signalword

Danger

hcodes

H242

pcodes

P210 - P234 - P235 - P240 - P370 + P378 - P403

Hazard Classifications

Self-react. C

Storage Class

5.2 - Organic peroxides and self-reacting hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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