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900653

Poly(ε-caprolactone)-b-poly(ethylene glycol)-b-poly(ε-caprolactone)

Name: Poly(ε-caprolactone)-<I>b</I>-poly(ethylene glycol)-<I>b</I>-poly(ε-caprolactone)
Brand: ALDRICH

5k-10k-5k

Synonym(s):

PCL-PEG-PCL, PCL-PEG-PCL triblock copolymer

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About This Item

Linear Formula:

H(OCH₂CH₂CH₂CH₂CH₂CO)_mO(CH₂CH₂O)_n(COCH₂CH₂CH₂CH₂CH₂O)_mH

NACRES:

NA.23

UNSPSC Code:

12162002

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Properties

Quality Level

100

form

powder or chunks

transition temp

flash point >230 °F, T_m 52-59 °C

storage temp.

2-8°C

Description

Application

Biocompatible, amphiphilic triblock polymer composed of a hydrophilic, central PEG block and two terminal hydrophobic PCL blocks. These materials have been used in drug delivery applications as well as thermoplastic elastomers. Well-defined materials with varying properties can be prepared by controlling the relative length of each polymer block. Hydroxyl termination allows for facile further chemical modification of these materials.

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Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Poly(caprolactone)-poly(ethylene glycol)-poly(caprolactone) (PCL-PEG-PCL) nanoparticles: a valuable and efficient system for in vitro and in vivo delivery of curcumin.

Manjii HK, et al.

Royal Society of Chemistry Advances, 6(17), 14403-14415 (2016)

Synthesis and microphase separation of biodegradable poly(ε-caprolactone)-poly(ethylene glycol)-poly(ε-caprolactone) multiblock copolymer films.

You JH, et al.

Macromolecular Research, 16(7), 609-613 (2008)

Synthesis and Characterization of PEG-PCL-PEG Triblock Copolymers as Carriers of Doxorubicin for the Treatment of Breast Cancer.

Cuong NV, et al.

Journal of Applied Polymer Science, 117, 3694-3703 (2010)

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Global Trade Item Number

SKU	GTIN
900653-500MG	04061833250662