900683
2-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-amine
95%
Synonym(s):
Amino diazirine alkyne, Probe building block
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About This Item
Empirical Formula (Hill Notation):
C7H11N3
CAS Number:
Molecular Weight:
137.18
UNSPSC Code:
12352116
MDL number:
NACRES:
NA.21
Assay:
95%
Form:
liquid
SMILES string
NCCC1(N=N1)CCC#C
InChI key
FMCIBERQJQEYIZ-UHFFFAOYSA-N
assay
95%
form
liquid
storage temp.
−20°C
Quality Level
Application
2-(3-(But-3-yn-1-yl)-3H-diazirin-3-yl)ethan-1-amine is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and amine synthetic handle. When appended to a ligand or pharmacophore through its amine linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
Other Notes
Technology Spotlight: Trifuctional Probe Building Blocks
Design and Synthesis of Minimalist Terminal Alkyne-Containing Diazirine Photo-Crosslinkers and Their Incorporation into Kinase Inhibitors for Cell- and Tissue-Based Proteome Profiling
"Minimalist" Cyclopropene-Containing Photo-Cross-Linkers Suitable for Live-Cell Imaging and Affinity-Based Protein Labeling
signalword
Danger
hcodes
Hazard Classifications
Self-react. C
Storage Class
5.2 - Organic peroxides and self-reacting hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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