900848
4-Amino-2-trimethylsilanylethynyl-benzenesulfonyl fluoride
Synonym(s):
Amino sulfonyl fluoride TMS-alkyne, Probe building block
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About This Item
Empirical Formula (Hill Notation):
C11H14FNO2SSi
CAS Number:
Molecular Weight:
271.38
UNSPSC Code:
12352200
NACRES:
NA.22
Form:
liquid
SMILES string
NC1=CC=C(S(=O)(F)=O)C(C#C[Si](C)(C)C)=C1
form
liquid
availability
available only in USA
storage temp.
−20°C
Application
Used for chemical probe synthesis, this trifunctional building block contains an aryl sulfonyl fluoride group, alkyne tag, and amine synthetic handle. When appended to a ligand or pharmacophore through its amine linker, this building block allows for SuFEx-enabled, context-specific covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.
signalword
Danger
hcodes
Hazard Classifications
Self-react. C
Storage Class
5.2 - Organic peroxides and self-reacting hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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