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900862

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol

Name: (4-(3-(Trifluoromethyl)-3<I>H</I>-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol
Brand: ALDRICH

Synonym(s):

Hydroxyl diazirine TMS-alkyne, Probe building block

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About This Item

Empirical Formula (Hill Notation):

C₁₄H₁₅F₃N₂OSi

CAS Number:

2187374-13-4

Molecular Weight:

312.36

UNSPSC Code:

12352200

NACRES:

NA.22

Assay:

≥95%

Form:

powder or crystals

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Properties

assay

≥95%

form

powder or crystals

storage temp.

−20°C

SMILES string

OCC1=CC=C(C2(N=N2)C(F)(F)F)C=C1C#C[Si](C)(C)C

Description

Application

(4-(3-(Trifluoromethyl)-3H-diazirin-3-yl)-2-((trimethylsilyl)ethynyl)phenyl)methanol is used for chemical probe synthesis, this trifunctional building block contains a light-activated diazirine, alkyne tag, and hydroxyl synthetic handle. When appended to a ligand or pharmacophore through its hydroxyl linker, this building block allows for UV light-induced covalent modification of a biological target with potential for downstream applications via the alkyne tag. Use alone or in parallel with other multi-functional building blocks to discover the optimal probe for your chemical biology experiments.

Other Notes

Technology Spotlight: Trifunctional Probe Building Blocks

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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