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Merck
CN

900883

NIR-II dye

Synonym(s):

Near IR fluorescent dye

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About This Item

NACRES:
NA.23
UNSPSC Code:
41116100
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description

Mass extinction co-efficient: 3.5 Lg-1cm-1, viscous solid or liquid

form

liquid

λmax

780-810 nm

fluorescence

λem ~1050 nm, quantum yield ~2% (NIR emission)

storage temp.

2-8°C

General description

The NIR-II Dye is a high-performance near-infrared fluorescent dye designed for advanced imaging applications. With a mass extinction coefficient of 3.5 Lg-1cm-1, this dye exhibits excellent solubility in common buffers, serum, and blood, making it highly versatile for biological studies. It has a maximum absorption wavelength ( λmax) ranging from 780 to 810 nm, and emits fluorescence around 1050 nm with a quantum yield of approximately 2%. Ideal for in vivo imaging, this dye can be used effectively in various biological contexts.

Preparation Note: For optimal results, store the NIR-II Dye in a dark environment at 4 °C. It is stable in phosphate-buffered saline (PBS) and miscible with common buffers and serum. When using for in vivo imaging, it is recommended to inject approximately 100-150 μg in a 200 μL solution for typical applications, such as imaging in nude mice. Ensure all handling is performed under appropriate safety conditions.

Features and Benefits

  • High Sensitivity: The dye is specifically formulated for near-infrared applications, providing enhanced sensitivity for imaging.
  • Versatile Solubility: Stable in various biological environments, including PBS, serum, and blood, facilitating diverse research applications.
  • Optimal Excitation and Emission: Suitable excitation wavelengths of 785 nm and 808 nm with emission peaks around 1050 nm, ideal for deep tissue imaging.
  • Quantum Yield: A quantum yield of ~2%, which is significantly higher than common alternatives, enhancing imaging quality and clarity.
  • Ease of Use: Designed for straightforward application in in vivo studies, making it a practical choice for researchers in the field.


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Storage Class

10 - Combustible liquids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



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