901185
3,3′-Diethoxypropyl methacrylate
≥98.0%, contains ≤100 ppm MEHQ as inhibitor
Synonym(s):
3,3-Diethoxypropyl 2-methylprop-2-enoate, DEPMA, Diethoxypropyl methacrylate
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About This Item
Empirical Formula (Hill Notation):
C11H20O4
CAS Number:
Molecular Weight:
216.27
MDL number:
UNSPSC Code:
12162002
NACRES:
NA.23
Assay
≥98.0%
form
liquid
contains
≤100 ppm MEHQ as inhibitor
color
colorless to pale yellow
shipped in
wet ice
storage temp.
−20°C
InChI
1S/C11H20O4/c1-5-13-10(14-6-2)7-8-15-11(12)9(3)4/h10H,3,5-8H2,1-2,4H3
InChI key
CPARKAXEDHCHNX-UHFFFAOYSA-N
Application
3,3′-Diethoxypropyl methacrylate is a methacrylate monomer used in the synthesis of the pH-responsive polymer poly(3,3′-diethoxypropyl methacrylate) (PDEPMA). PDEPMA contains acetal groups, which upon exposure to acid in solution hydrolyze to form aldehyde groups that can be further reacted via chemical conjugation with biomolecules or other small molecules. Due to their responsive nature and well-controlled deprotection reactions, these materials have been used in a wide variety of biomedical applications such as surface patterning for sensors, the synthesis of polymer-biomolecule conjugates, and drug delivery applications.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
161.6 °F
Flash Point(C)
72 °C
Regulatory Information
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Jungyeon Hwang et al.
Journal of controlled release : official journal of the Controlled Release Society, 122(3), 279-286 (2007-06-30)
Polymers with reactive side chains and narrow molecular weight distributions were synthesized by reversible addition-fragmentation chain transfer (RAFT) polymerization, and the potential to utilize these polymers to prepare drug carriers was demonstrated. p-Nitrophenyl methacrylate (NPMA) and diethoxypropyl methacrylate (DEPMA) were
Karen L Christman et al.
Langmuir : the ACS journal of surfaces and colloids, 21(18), 8389-8393 (2005-08-24)
Protein and peptide microarrays are popular candidates for medical diagnostics because of the possibility for high sensitivity and simultaneous marker screening. To realize the potential of these arrays, new strategies for ligand patterning are needed. We report a method for
Anja S Goldmann et al.
Macromolecular rapid communications, 34(10), 810-849 (2013-04-30)
The establishment of advanced living/controlled polymerization protocols allows for engineering synthetic polymers in a precise fashion. Combining advanced living/controlled polymerization techniques with highly efficient coupling chemistries facilitates quantitative, modular, and orthogonal functionalization of synthetic polymer strands at their chain termini
The emergence of oxime click chemistry and its utility in polymer science.
Collins J, et al.
Polym. Chem., 7, 3812-3826 (2016)
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