Key Documents

View All Documentation

901215

Ephos

Name: Ephos
Brand: ALDRICH

≥95%, powder or crystals

Synonym(s):

Dicyclohexyl(3-isopropoxy-2′,4′,6′-triisopropyl-[1,1′-biphenyl]-2-yl)phosphane

Select a Size

Change View

About This Item

Empirical Formula (Hill Notation):

C₃₆H₅₅OP

CAS Number:

2118959-55-8

Molecular Weight:

534.80

MDL number:

MFCD31619192

UNSPSC Code:

12352128

NACRES:

NA.22

Technical Service

Need help? Our team of experienced scientists is here for you.

Let Us Assist

Properties

Product Name

Ephos, ≥95%

Quality Level

100

product line

Buchwald Ligand

assay

≥95%

form

powder or crystals

reaction suitability

reaction type: Buchwald-Hartwig Cross Coupling Reaction, reaction type: Heck Reaction, reaction type: Hiyama Coupling, reaction type: Negishi Coupling, reaction type: Sonogashira Coupling, reaction type: Stille Coupling, reaction type: Suzuki-Miyaura Coupling, reagent type: catalyst
reaction type: Cross Couplings, reagent type: ligand

greener alternative product score

old score: 41
new score: 28
Find out more about DOZN™ Scoring

greener alternative product characteristics

Atom Economy
Safer Solvents and Auxiliaries
Inherently Safer Chemistry for Accident Prevention
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

mp

161-162 °C

functional group

phosphine

greener alternative category

Re-engineered

SMILES string

P(C4CCCCC4)(C3CCCCC3)c1c(cccc1c2c(cc(cc2C(C)C)C(C)C)C(C)C)OC(C)C

InChI

1S/C36H55OP/c1-24(2)28-22-32(25(3)4)35(33(23-28)26(5)6)31-20-15-21-34(37-27(7)8)36(31)38(29-16-11-9-12-17-29)30-18-13-10-14-19-30/h15,20-27,29-30H,9-14,16-19H2,1-8H3

InChI key

FDAKNRLXSJBEFL-UHFFFAOYSA-N

Description

General description

We are committed to bringing you Greener Alternative Products that adhere to one of the four categories of Greener Alternatives. This product belongs to the category of Re-engineered Products, demonstrating key improvements in Green Chemistry Principles such as "Atom Economy", "Safer Solvents and Auxiliaries", and "Inherently Safer Chemistry for Accident Prevention". Click here to view its DOZN scorecard.

Application

Ephos can be used as a ligand in the palladium-catalyzed synthesis of 4-arylaminothiazoles and 2-arylaminooxazoles.

Buchwald ligand for Pd-catalyzed C–N cross-coupling between primary amines and aryl
halides to form 2-arylaminooxazoles. Catalyst system was reported with NaOPh (CDS001581).

Other Notes

Mechanistic Insight Leads to a Ligand That Facilitates the Pd-Catalyzed Formation of 2-(Hetero)Arylaminooxazoles and 4-(Hetero)Arylaminothiazoles

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Choose from one of the most recent versions:

Certificates of Analysis (COA)

Lot/Batch Number

Don't see the Right Version?

If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

Search for a COA

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Global Trade Item Number

SKU	GTIN
901215-1G	04061835508778
901215-250MG	04061835505302