901397
Poly(ethylene glycol) linear dendrimer
NHBoc terminated, PEG Mn 6000, generation 4
Synonym(s):
Dendron bifunctionalized PEG, PFD-G4-PEG6k-NHBoc, Polyethylene glycol
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About This Item
Empirical Formula (Hill Notation):
C678H1202N32O323
Molecular Weight:
14970.82
NACRES:
NA.23
UNSPSC Code:
51171641
General description
- Polymer architecture: Dendron-functionalized PEG
- Generation: 4
- PEG Average Mn: 6,000
- End group functionality: Boc-protected amine
- No. surface groups: 32
- Calculated mol. wt.: 14970.98 g/mol
- Boc: tert-Butyloxycarbonyl
- Bis-MPA: 2,2-bis(hydroxymethyl)propionic acid
Application
Bis-MPA (or 2,2-bis(methylol)propionic acid) is an aliphatic, pro-chiral molecule comprised of two hydroxyls and one carboxylic group that has been used in the synthesis of many different types of polymers. Dendrons synthesized from bis-MPA are biodegradable and have low cytotoxicity, making them well suited for use in biological research applications. These materials have been used in many applications such as signal amplification in bioassays and in drug delivery applications. PEG-core dendrimers feature excellent solubility in water and a high degree of functionality per PEG chain, making them strong candidates for advanced drug delivery systems or as targeting vessels. Additionally, the terminal amine groups can readily be used in EDC or DCC coupling reactions (after Boc deprotection) with carbonyl-containing compounds, to yield highly functionalized materials for a variety of biomedical applications.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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