901699
3-Mercaptopropanyl-N-hydroxysuccinimide ester
>95%
Synonym(s):
NHS ester
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About This Item
Empirical Formula (Hill Notation):
C7H9NO4S
CAS Number:
Molecular Weight:
203.22
UNSPSC Code:
12352005
NACRES:
NA.23
MDL number:
assay
>95%
form
solid or liquid
reaction suitability
reagent type: linker
technique(s)
targeted protein degradation: suitable
color
colorless to yellow
functional group
NHS ester, thiol
storage temp.
2-8°C
SMILES string
SCCC(ON1C(CCC1=O)=O)=O
InChI
1S/C7H9NO4S/c9-5-1-2-6(10)8(5)12-7(11)3-4-13/h13H,1-4H2
InChI key
UTBOEPMMEANMPS-UHFFFAOYSA-N
Application
3-Mercaptopropanyl-N-hydroxysuccinimide ester can be used in the synthesis of diaminobutane (DAB) based dendrimers for the formation of an ultrafiltration membrane for the removal of heavy metals.
3-Mercaptopropanyl-N-hydroxysuccinimide ester is an aliphatic, heterobifunctional crosslinking reagent. Due to the functional groups, this material can be used in a multitude of applications, such as the synthesis of protien-polymer conjugates and the synthesis of functionalized quantum dots. In addition to use as a crosslinking agent, this material can also be used to install functional groups post-polymerization. The terminal N-hydroxysuccinimide (NHS) ester can react with amines while the terminal thiol can react with thiols, alkenes, and alkynes. The free thiol can also be used to form self-assembled monolayers (SAMs) on gold surfaces.
Signal Word
Warning
Hazard Codes
Precautionary Statements
Hazard Classifications
Flam. Liq. 3
Storage Class
3 - Flammable liquids
Flash Point (°F)
110.0 °F
Flash Point (°C)
43.33 °C
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