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Merck
CN

901699

3-Mercaptopropanyl-N-hydroxysuccinimide ester

>95%

Synonym(s):

NHS ester

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About This Item

Empirical Formula (Hill Notation):
C7H9NO4S
CAS Number:
Molecular Weight:
203.22
UNSPSC Code:
12352005
NACRES:
NA.23
MDL number:
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assay

>95%

form

solid or liquid

reaction suitability

reagent type: linker

color

colorless to yellow

functional group

NHS ester, thiol

storage temp.

2-8°C

SMILES string

SCCC(ON1C(CCC1=O)=O)=O

InChI

1S/C7H9NO4S/c9-5-1-2-6(10)8(5)12-7(11)3-4-13/h13H,1-4H2

InChI key

UTBOEPMMEANMPS-UHFFFAOYSA-N

Application

3-Mercaptopropanyl-N-hydroxysuccinimide ester can be used in the synthesis of diaminobutane (DAB) based dendrimers for the formation of an ultrafiltration membrane for the removal of heavy metals.
3-Mercaptopropanyl-N-hydroxysuccinimide ester is an aliphatic, heterobifunctional crosslinking reagent. Due to the functional groups, this material can be used in a multitude of applications, such as the synthesis of protien-polymer conjugates and the synthesis of functionalized quantum dots. In addition to use as a crosslinking agent, this material can also be used to install functional groups post-polymerization. The terminal N-hydroxysuccinimide (NHS) ester can react with amines while the terminal thiol can react with thiols, alkenes, and alkynes. The free thiol can also be used to form self-assembled monolayers (SAMs) on gold surfaces.


pictograms

Flame

signalword

Warning

hcodes

Hazard Classifications

Flam. Liq. 3

Storage Class

3 - Flammable liquids

wgk

WGK 3

flash_point_f

110.0 °F

flash_point_c

43.33 °C

Regulatory Information

危险化学品

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Inclusion of thiol DAB dendrimer/CdSe quantum dots based in a membrane structure: Surface and bulk membrane modification
Algarra M, et al.
Electrochimica Acta, 89, 652-659 (2013)
Characterization of an engineered cellulose based membrane by thiol dendrimer for heavy metals removal
Algarra M, et al.
Chemical Engineering Journal, 253, 472-477 (2014)



Global Trade Item Number

SKUGTIN
901699-5G04061834899099
901699-1G04061834899082