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Merck
CN

901803

Fluorescent nanodiamond

nitrogen vacancy ~3 ppm, 140 nm avg. part. size, hydroxyl functionalized, PEG 3000 coated, 1 mg/mL in deionized water

Synonym(s):

Fluorescent nanoparticles, Nanodiamonds

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About This Item

NACRES:
NA.23
UNSPSC Code:
12352302

Key Documents

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form

nanoparticles

composition

nitrogen vacancy, ~3 ppm

concentration

1 mg/mL in deionized water

avg. part. size

140 nm

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General description

Fluorescent nanodiamond (nitrogen vacancy ~3 ppm, 140 nm avg. part. size, hydroxyl functionalized, PEG 3000 coated, 1 mg/mL in deionized water), a biocompatible carbon-based nanomaterial, has interesting properties like excellent photostability, low toxic and facile surface functionalizability. It can be used for a variety of biological applications.

Application

Nanodiamonds (NDs) containing NV color centers exhibit fluorescence in red/near infra-red (NIR) region. The fluorescence in NDs originates from nitrogen vacancies and, unlike quantum dots and organic dyes, NDs do not photobleach. Fluorescent NDs find applications in background-free imaging, flow cytometry, super-resolution imaging etc. The PEG coated NDs exhibit reduced non-specific binding and are well suited for biomedical applications.

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Nanodiamond bioconjugate probes and their collection by electrophoresis.
S. C. Hens et al.,
Diamond and Related Materials, 17, 1858-1858 (2008)
Functionality is Key: Recent Progress in the Surface Modification of Nanodiamond.
A. Krueger a4nd D. Lang
Advances in Functional Materials, 22, 890-890 (2012)
Highly Fluorescent Nanodiamonds Protein-Functionalized for Cell Labeling and Targeting
B. Chang et al.,
Advances in Functional Materials, 23, 5737-5737 (2013)
The long-term stability and biocompatibility of fluorescent nanodiamond as an in vivo contrast agent
Vaijayanthimala V, et al.
Biomaterials, 33(31), 7794-7802 (2012)
Nanodiamond-mediated drug delivery and imaging: Challenges and opportunities.
V. Vaijayanthimala et al.,
Expert Opinion on Drug Delivery, 12, 1-1 (2014)
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