904643
Thiol functionalized gelatin
Synonym(s):
Functionalized gelatin, Gelatin thiol, Gelatin-SH• Gel-SH, SH functionalized gelatin, Thiol functionalized gelatin, Thiol gelatin, Thiolated gelatin, Gelatin / GelMA & derivatives
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About This Item
NACRES:
NA.23
UNSPSC Code:
12352105
description
NMR: Conforms to structure, Thiol content 150-350 μmol/g
assay
150-350 μmol/g (Free Thiol Concentration by UVVI, UV-vis)
form
powder
color
white to pale yellow
storage temp.
−20°C
Application
Gelatin has received significant attention in the biomedical field due to its inherent bioactivity. Functionalized gelatin can be cross-linked with the formation of covalent bonds into highly crosslinked structures, such as hydrogels. Recent literature suggests that radical-mediated polymerized hydrogels may not be ideal for cell and protein encapsulation due to radical-mediated damage, hindered molecular transport, or altered cell-cell/cell-material interactions. Thiol-modified gelatin can be used to form hydrogels with multifunctional norbornene or allyl crosslinkers via thiol-ene click or Michael-addition reactions.
To improve solubility in water, heat to 40°C and stir for 10-15 minutes.
Disclaimer
Material should be handled under nitrogen - air/oxygen & moisture are to be avoided.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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