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Merck
CN

906840

Poly(L-lactide-co-caprolactone)

lactide:caprolactone 90:10, viscosity 1.7 dL/g 

Synonym(s):

PCL-PLLA, PLLA-PCL

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About This Item

Linear Formula:
CH3(C6H10O2)m(C6H8O4)nCH3
UNSPSC Code:
12162002
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form

chunks

feed ratio

lactide:caprolactone 90:10

color

white to off-white

viscosity

1.7 dL/g

storage temp.

−20°C

General description

Poly(L-lactide-co-caprolactone) (PCL-PLLA) is a biodegradable polymer which can be synthesized by bulk ring-opening copolymerization of L-lactide and ε-caprolactone. Its properties include flexibility, biocompatibility and controlled degradation process.

Application

PCL-PLLA can be used for a variety of applications such as tissue engineering, bone fixation devices and surgical sutures.
Poly(L-lactide-co-caprolactone) (PLLA-PCL) is a biodegradable copolymer. poly(L-lactide) exhibits a high modulus and has been often copolymerized with PCL to improve the mechanical properties of PCL, and increase degradation rate of the resulting polymer. PLLA-PCL has been used in tissue engineering, 3D bioprinting and drug delivery research applications.


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Storage Class

13 - Non Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Regulatory Information

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Comparison of plasma and chemical modifications of poly-L-lactide-co-caprolactone scaffolds for heparin conjugation
Hsieh Y, et al.
Bio-medical materials and engineering, 12(6), 065004-065004 (2017)
Preparation of a poly (L-lactide-co-caprolactone) copolymer using a novel tin (II) alkoxide initiator and its fiber processing for potential use as an absorbable monofilament surgical suture
Ruengdechawiwat S, et al.
International Journal of Polymeric Materials and Polymeric Biomaterials, 65(6), 277-284 (2016)
Application of a bilayer tubular scaffold based on electrospun poly (L-lactide-co-caprolactone)/collagen fibers and yarns for tracheal tissue engineering
Wu T, et al.
Journal of materials chemistry. B, 5(1), 139-150 (2017)



Global Trade Item Number

SKUGTIN
906840-5G04054839937309