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Merck
CN

908843

Poly(lactide-co-glycolide)-b-poly(ethylene glycol)-b-poly(lactide-co-glycolide)

average Mn (1,600-1,500-1,600), lactide:glycolide 75:25

别名:

PLGA-PEG-PLGA

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关于此项目

线性分子式:
H((C3H4O2)x(C2H2O2)y)m((C2H4O)z)nO((C3H4O2)x(C2H2O2)y)mH
NACRES:
NA.23
UNSPSC Code:
51171641
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form

semisolid

feed ratio

lactide:glycolide 75:25

mol wt

PEG average Mn 1,500 (by NMR), PLGA average Mn 3,200 (by NMR), average Mn (1,600-1,500-1,600)

color

white to tan

PDI

≤2.0, <1.1 (Typical PEG PDI )

storage temp.

−20°C

Application

PLGA-PEG-PLGA is an amphiphilic triblock copolymer which can self-assemble into micelles in aqueous medium due to the hydrophobic interactions present in the hydrophobic segments. The PEG segment imparts hydrophilicity and improves the biocompatibility of the copolymer. The PLGA segment forms a hydrophobic core and can solubilize hydrophobic drugs. These copolymers are widely used as nanocarriers for the sustained release of drugs. Also this polymer exhibits thermogelation behavior. When applied in biomedical applications, the temperature responsive nature of the copolymer can be tuned to induce an in situ gelation at physiological temperature to provide controlled drug release. These materials have been explored for biomedical applications as temperature-responsive biodegradable systems for drug delivery, tissue engineering and wound healing.


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存储类别

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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