910791
Poly(ethylene glycol)-block-polyethyleneimine
PEG Mn 750, PEI Mn 15k
别名:
Linear poly(ethylene glycol)-block-polyethylenimine, Nanopatterning, PEG-b-PEI, PEG-PEI, block-copolymers
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关于此项目
线性分子式:
CH3(C2H4O)m(C2H5N)nOH
NACRES:
NA.23
UNSPSC Code:
12162002
form
powder or solid
mol wt
PEG Mn 750, PEG Mw 750 Da, PEI Mn 15k, PEI Mw 10,000 Da
color
white to pale yellow
storage temp.
2-8°C
Application
Gene therapy using polymeric nonviral vectors promises considerable advances in the treatment of many genetic and acquired diseases due to the carrier safety and low immunogenicity profiles. Poly(ethyleneimine) is one of the most commonly used cationic polymers for gene delivery applications. Copolymers of PEI and hydrophilic poly(ethylene glycol) have been designed to provide a stealth-like shield around polymer/DNA complexes, reducing nonspecific interactions, inhibiting activation of the reticuloendothelial system, and prolonging the half-life of the complexes in the blood.
存储类别
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable