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Merck
CN

910813

mPEG24-NHS

Synonym(s):

Methoxypolyethylene glycol acetic acid N-succinimidyl ester, mPEG NHS

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About This Item

Empirical Formula (Hill Notation):
C56H107NO29
CAS Number:
174569-25-6
Molecular Weight:
1258.44
UNSPSC Code:
43211915
NACRES:
NA.23
MDL number:
MFCD28385538

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SMILES string

N1(C(=O)CCC1=O)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC

InChI

1S/C56H107NO29/c1-61-6-7-63-10-11-65-14-15-67-18-19-69-22-23-71-26-27-73-30-31-75-34-35-77-38-39-79-42-43-81-46-47-83-50-51-85-53-52-84-49-48-82-45-44-80-41-40-78-37-36-76-33-32-74-29-28-72-25-24-70-21-20-68-17-16-66-13-12-64-9-8-62-5-4-56(60)86-57-54(58)

InChI key

IXVOIXFTBGZAJR-UHFFFAOYSA-N

assay

95% (HPLC)

form

solid

mol wt

average Mn 1,250 (by NMR)

reaction suitability

reagent type: chemical modification reagent
reactivity: amine reactive

color

white to off-white

Ω-end

NHS ester

α-end

methoxy

polymer architecture

shape: linear
functionality: monofunctional

storage temp.

−20°C

Related Categories

Application

Polyethylene glycols (PEGs) are FDA approved hydrophilic polymers. They are non-toxic, non-immunogenic and non-antigenic, and are widely used in a variety of biomedical applications such as bioconjugation, drug delivery, surface functionalization, and tissue engineering. PEG-NHS is an amine reactive PEG that can react to amino groups of lysine(s) on proteins or other biologics; reaction occurs at room temperature in <1hr at pH 7-8. Stable linker between PEG and NHS ester.

Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

>230.0 °F

flash_point_c

> 110 °C

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