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Merck
CN

915637

Sigma-Aldrich

TissueFab® bioink Bone

support gel

Synonym(s):

3D Bioprinting, 3D printing, Bioink, TissueFab

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About This Item

UNSPSC Code:
12352201
NACRES:
NA.23

Key Documents

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description

suitable for 3D bioprinting applications

Quality Level

100

form

powder

color

white

application(s)

3D bioprinting

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Application

TissueFab® - Bone support bioink is suitable for printing bone scaffold or using as a supporting bioink for bone specific hydrogel/matrix bioink. It is formulated with optimal ratio of PCL and HAp, which shows excellent printability and osteogenic bioactivity. Polycaprolactone (PCL) is a synthetic biodegradable polymer that has been widely used as 3D printed bone scaffold material. Hydroxyapatite (HAp) has a chemical similarity with the mineralized phase of bone which accounts for their excellent biocompatibility and osteoinductive and osteoconductive properties favorable for bone regeneration.

Packaging

5g in glass bottle

Legal Information

TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Regulatory Information

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Boontharika Chuenjitkuntaworn et al.
Journal of biomedical materials research. Part A, 94(1), 241-251 (2010-02-19)
Polycaprolactone (PCL) is a synthetic biodegradable polymer that has been approved for use as bone graft substitutes. In this study, PCL scaffolds incorporating hydroxyapatite (HAp) particles were fabricated by combined solvent casting and particulate leaching techniques. The average pore dimension
Liang Dong et al.
Scientific reports, 7(1), 13412-13412 (2017-10-19)
Synthetic polymeric scaffolds are commonly used in bone tissue engineering (BTE) due to their biocompatibility and adequate mechanical properties. However, their hydrophobicity and the lack of specific cell recognition sites confined their practical application. In this study, to improve the
Su A Park et al.
Bioprocess and biosystems engineering, 34(4), 505-513 (2010-12-21)
For tissue engineering and regeneration, a porous scaffold with interconnected networks is needed to guide cell attachment and growth/ingrowth in three-dimensional (3D) structure. Using a rapid prototyping (RP) technique, we designed and fabricated 3D plotting system and three types of
Hyung-Chul Pae et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 107(4), 1254-1263 (2018-10-10)
Defect-specific bone regeneration using 3-dimensional (3D) printing of block bone has been developed. Polycaprolactone (PCL) is biocompatible polymer that can be used as 3D scaffold. The aim of this study is to assess the biocompatibility and osteogenic efficacy of 3D
Mitchell A Kuss et al.
RSC advances, 7(47), 29312-29320 (2017-07-04)
Reconstruction of complex, craniofacial bone defects often requires autogenous vascularized bone grafts, and still remains a challenge today. In order to address this issue, we isolated the stromal vascular fraction (SVF) from adipose tissues and maintained the phenotypes and the

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