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918962

Poly(ethylene glycol) methyl ether-block-poly(D,L lactide)

Name: Poly(ethylene glycol) methyl ether-<I>block-</I>poly(<SC>D</SC>,<SC>L</SC> lactide)
Brand: ALDRICH

PEG average M_n 5000, PDLA average M_n 50000

Synonym(s):

Biodegradable, Block copolymer, Drug delivery, PEG-PLA, PLLA, mPEG-PLA, mPEG-PLLA

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About This Item

Linear Formula:

HO[CH(CH₃)COO]_m[CH₂CH₂O]_nCH₃

NACRES:

NA.23

UNSPSC Code:

12352106

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Properties

form

solid

Quality Segment

100

mol wt

PDLA average M_n 50,000 (by NMR), PDLA average M_n 50000, PEG average M_n 5,000 (by NMR), PEG average M_n 5000

color

white to yellow

storage temp.

2-8°C

Description

Application

Poly(ethylene glycol) methyl ether-block-poly(D,L lactide) is an amphiphilic, diblock copolymer composed of a hydrophilic PEG block and a hydrophobic PLA block. These biodegradable, biocompatible polymers can self-assemble to form nanoparticles, such as micelles and polymersomes, in both aqueous and non-aqueous media. Due to these properties, these polymers are widely used in polymeric nanoparticle formulation to achieve controlled and targeted delivery of therapeutic agents (e.g. APIs, genetic material, peptides, vaccines, and antibiotics).

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Storage Class

11 - Combustible Solids

wgk

WGK 3

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