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Merck
CN

920428

Sigma-Aldrich

Methoxypolyethylene glycol

average MN 1,000 (by NMR), glycol propyl amine, methoxy

Synonym(s):

PEG amine, Poly(ethylene) glycol amine, Polyethylene glycol, mPEG NH2, mPEG amine

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About This Item

Linear Formula:
CH3(OCH2CH2)nOCH2CH2CH2NH2
UNSPSC Code:
12352116
NACRES:
NA.23
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Product Name

Methoxypolyethylene glycol propyl amine 1,000,

form

semisolid

Quality Level

mol wt

average Mn 1,000 (by NMR)

color

white to off-white

Ω-end

amine

α-end

methoxy

polymer architecture

shape: linear
functionality: monofunctional

Application

Methoxypolyethylene glycol propyl amine 1,000 is a pegylation agent used to conjugate proteins to reduce immunogenicity and prolong serum half-life of proteins and enzymes.

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Regulatory Information

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A Ton J Dirks et al.
Bioconjugate chemistry, 20(6), 1129-1138 (2009-05-21)
The Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) has recently proven to be a powerful synthetic tool in various fields of chemistry, including protein-polymer conjugation. In this article, we describe a fluorogenic CuAAC, which allows for efficient monitoring of protein-polymer conjugation. We show

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