920819
mPEG functionalized alginate
5% +/- 2% PEGylation, PEG average Mn 1k
Synonym(s):
PEGylated alginate, PEGylated low viscosity alginate, PEGylated sodium alginate
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About This Item
Linear Formula:
{C6H7O5[NHCH2CH2CH2O(CH2CH2O)xCH3]}n(C6H7O6Na)m
NACRES:
NA.23
UNSPSC Code:
12352201
Product Name
mPEG functionalized alginate, 5% +/- 2% PEGylation, PEG average Mn 1k
form
(solid or chunk(s) or fiber)
mol wt
PEG average Mn 1k
color
white to off-white
storage temp.
2-8°C
Quality Level
Related Categories
Application
Alginate is biocompatible and biodegradable, and forms hydrogels in the presence of divalent cations (e.g., Ca2+, Ba2+) under mild temperature and pH conditions. mPEG functionalized alginate can used to tune the stress relaxation of alginate hydrogels, and can used to fabricate microparticles with better mechanical properties.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Solène Passemard et al.
Biomacromolecules, 18(9), 2747-2755 (2017-07-26)
The production of hydrogel microspheres (MS) for cell immobilization, maintaining the favorable properties of alginate gels but presenting enhanced performance in terms of in vivo durability and physical properties, is desirable to extend the therapeutic potential of cell transplantation. A
Varying PEG density to control stress relaxation in alginate-PEG hydrogels for 3D cell culture studies
Nam S., et al.
Biomaterials, 200, 15-24 (2019)
Redouan Mahou et al.
Materials (Basel, Switzerland), 7(1), 275-286 (2014-01-09)
The progress of medical therapies, which rely on the transplantation of microencapsulated living cells, depends on the quality of the encapsulating material. Such material has to be biocompatible, and the microencapsulation process must be simple and not harm the cells.
Xu Jia et al.
ACS biomaterials science & engineering, 2(9), 1641-1648 (2016-09-12)
Theranostic nanomedicine has recently emerged as an appealing approach for tumor chemotherapy. Here, for the first time, fluorescent carbon dots (Cdots) were used as cross-linker for tumor theranostic nanoparticles. Novel theranostic nanoparticles of approximately 27 nm with a doxorubicin (DOX)
Sungmin Nam et al.
Biomaterials, 200, 15-24 (2019-02-12)
Hydrogels are commonly used as artificial extracellular matrices for 3D cell culture and for tissue engineering. Viscoelastic hydrogels with tunable stress relaxation have recently been developed, and stress relaxation in the hydrogels has been found to play a key role
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