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925462

Maleimide poly(ethylene glycol)-block-poly(lactide-co-glycolide)

Name: Maleimide poly(ethylene glycol)-<I>block</I>-poly(lactide-<I>co</I>-glycolide)
Brand: ALDRICH

PEG average M_n 5,000, PLGA average M_n 15,000, lactide:glycolide 50:50

Synonym(s):

Maleimide-PEG-b-PLGA, Maleimide-PEG-PLGA

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About This Item

Linear Formula:

C₁₃H₁₉SN₂O₄(C₂H₄O)_nC₂H₄O[(C₂H₂O₂)_x(C₃H₄O₂)_y]_m

NACRES:

NA.23

UNSPSC Code:

12352111

eCl@ss:

32150917

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Properties

Quality Segment

100

feed ratio

50:50±5 (Lactide:Glycolide, by NMR), lactide:glycolide 50:50

mol wt

PEG M_n 4000-6000 g/mol (by NMR), PEG average M_n 5,000, PLGA M_n 12000-18000 g/mol, PLGA average M_n 15,000

suitability

conforms to structure for NMR

storage temp.

−20°C

Description

Application

Maleimide poly(ethylene glycol)-block-poly(lactide-co-glycolide) is a maleimide-functionalized, biocompatible, amphiphilic block copolymer. Due to its self-assembling properties, this material can be used in the formation of nanoparticles for drug delivery. Additionally, due to the maleimide-functionalization of the PEG block, this material can be used to rapidly covalently conjugate biomolecules, API, or targeting ligands. Potential uses include the targeted and/or controlled release of cancer drugs, anti-inflammatory drugs, antibiotics, or anesthetic agents.

Storage Class

11 - Combustible Solids

WGK

WGK 3

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