925659
Poly(ethylene glycol)-block-poly(lactide-alt-glycolide)
PEG average Mn 5,000, PLGA Mn 15,000
Synonym(s):
PEG-PLGA
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About This Item
Linear Formula:
CH3O(C2H4O)n(C5H6O4)mH
NACRES:
NA.23
UNSPSC Code:
12352112
form
powder, chunks or granules
Quality Segment
mol wt
PEG average Mn 5,000, PLGA Mn 15,000
storage temp.
2-8°C
Application
PEG-PLGA, is a biocompatible, amphiphilic block copolymer composed of a hydrophilic PEG block and a hydrophobic poly(lactide-alternative-glycolide) (PLGA) block. These materials have been used in control release and nanoparticle formulation for drug encapsulation and delivery applications.
Different from common Poly(lactide-co-glycolide) (PLGA) polymer, the lactic and glycolic units in Poly(lactide-alt-glycolide) block alternate in sequence in the polymer chain, and the molar ratio of lactic to glycolic units in the polymer is exactly 1:1.
Poly(lactide-alt-glycolide) exhibits excellent solubility in common organic solvents, such as acetonitrile, acetone, dioxane, DCM, and THF, providing great convenience for drug delivery researches and applications.
Different from common Poly(lactide-co-glycolide) (PLGA) polymer, the lactic and glycolic units in Poly(lactide-alt-glycolide) block alternate in sequence in the polymer chain, and the molar ratio of lactic to glycolic units in the polymer is exactly 1:1.
Poly(lactide-alt-glycolide) exhibits excellent solubility in common organic solvents, such as acetonitrile, acetone, dioxane, DCM, and THF, providing great convenience for drug delivery researches and applications.
Storage Class
11 - Combustible Solids
WGK
WGK 3
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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