926175
Glycol Chitosan Methacrylate
Degree of methacrylation ∼45%
Synonym(s):
Chitosan hydrogel, Crosslinkble chitosan, Glycol chitosan, Methacrylated glycol chitosan
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About This Item
Linear Formula:
[C14H25NO8]n [C10H17NO6]m
NACRES:
NA.23
UNSPSC Code:
12352201
Product Name
Glycol Chitosan Methacrylate, Degree of methacrylation ∼45%
form
powder
color
white to light yellow, light brown
suitability
conforms to structure for NMR
storage temp.
2-8°C
Quality Level
Related Categories
Application
Glycol chitosan is soluble at neutral pH and possesses potentially useful biological properties such as good biocompatibility accelerate wound healing, and antimicrobial properties, and it is less toxic and provide to stimulates chondrocyte growth at low concentrations. Methacrylated glycol chitosan is photo- and thermally cross-linkable and is used as a precursor for the preparation of hydrogels used in biomedical applications including drug delivery, tissue engineering, and 3D bioprinting.
Storage Class
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Regulatory Information
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Brian G Amsden et al.
Biomacromolecules, 8(12), 3758-3766 (2007-11-23)
Glycol chitosan is a derivative of chitosan that is soluble at neutral pH and possesses potentially useful biological properties. With the goal of obtaining biocompatible hydrogels for use as tissue engineering scaffolds or drug delivery depots, glycol chitosan was converted
K Y Lee et al.
Biomaterials, 16(16), 1211-1216 (1995-11-01)
Chitosan was selectively N-acylated with various carboxylic anhydrides, e.g., acetic, propionic, n-butyric, n-valeric and n-hexanoic anhydrides, in the presence of methanol. The degree of N-acylation of about 20-50% was obtainable without occurrence of gelation by using carboxylic anhydrides of 0.3-1.2
Modified chitosan hydrogels as drug delivery and tissue engineering systems: present status and applications
Tapan Kumar Giri Amrit Thakur, et al.
Acta Pharmaceutica Sinica. B, Volume 2, Issue 5, 439-449 (2012)
Eun Seok Ko et al.
Carbohydrate polymers, 245, 116496-116496 (2020-07-29)
Hydrogel systems that show self-healing ability after mechanical damage are receiving increasing attention. However, self-healing hydrogels suitable for biomedical applications are limited owing to complex preparation methods. Furthermore, few studies have demonstrated the self-healing property of ferrogels. In this study
Evaluation of the Properties of Soluble Chitosan and Chitosan Microspheres
Carreno-Gomez, B.; Duncan, R
International Journal of Pharmaceutics, 148 (2), 231-240 (1997)
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