92893
3,6,9-Trioxaundecanedioic acid
technical, ≥70% (T)
Synonym(s):
O,O′-Oxydiethylene-diglycolic acid
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About This Item
Empirical Formula (Hill Notation):
C8H14O7
CAS Number:
Molecular Weight:
222.19
UNSPSC Code:
12352106
NACRES:
NA.22
PubChem Substance ID:
EC Number:
237-655-9
Beilstein/REAXYS Number:
1962084
MDL number:
Assay:
≥70% (T)
Form:
liquid
InChI key
HJZZQNLKBWJYPD-UHFFFAOYSA-N
InChI
1S/C8H14O7/c9-7(10)5-14-3-1-13-2-4-15-6-8(11)12/h1-6H2,(H,9,10)(H,11,12)
SMILES string
OC(=O)COCCOCCOCC(O)=O
grade
technical
assay
≥70% (T)
form
liquid
reaction suitability
reaction type: Pegylations, reagent type: cross-linking reagent
impurities
~10% water
Quality Level
density
1.3 g/mL at 20 °C (lit.)
Related Categories
General description
3,6,9-Trioxaundecanedioic, acid also known as tetraglycolic acid, is a water miscible hydrophilic cross-linking reagent, widely utilized in PEGylation reactions.
Application
3,6,9-Trioxaundecanedioic acid is used as a cross linking agent in the synthesis of biodegradable, kojic acid-based poly(carbonate-esters).
signalword
Danger
hcodes
Hazard Classifications
Eye Dam. 1
Storage Class
10 - Combustible liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
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Biodegradable kojic acid-based polymers: controlled delivery of bioactives for melanogenesis inhibition
JJ Faig
Biomacromolecules, 18, 363-373 (2017)
Jonathan J Faig et al.
Biomacromolecules, 18(2), 363-373 (2016-12-28)
Kojic acid (KA) is a naturally occurring fungal metabolite that is utilized as a skin-lightener and antibrowning agent owing to its potent tyrosinase inhibition activity. While efficacious, KA's inclination to undergo pH-mediated, thermal-, and photodegradation reduces its efficacy, necessitating stabilizing
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