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Merck
CN

92893

3,6,9-Trioxaundecanedioic acid

technical, ≥70% (T)

Synonym(s):

O,O′-Oxydiethylene-diglycolic acid

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About This Item

Empirical Formula (Hill Notation):
C8H14O7
CAS Number:
Molecular Weight:
222.19
UNSPSC Code:
12352106
NACRES:
NA.22
PubChem Substance ID:
EC Number:
237-655-9
Beilstein/REAXYS Number:
1962084
MDL number:
Assay:
≥70% (T)
Form:
liquid
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grade

technical

Quality Level

assay

≥70% (T)

form

liquid

reaction suitability

reaction type: Pegylations, reagent type: cross-linking reagent

impurities

~10% water

density

1.3 g/mL at 20 °C (lit.)

SMILES string

OC(=O)COCCOCCOCC(O)=O

InChI

1S/C8H14O7/c9-7(10)5-14-3-1-13-2-4-15-6-8(11)12/h1-6H2,(H,9,10)(H,11,12)

InChI key

HJZZQNLKBWJYPD-UHFFFAOYSA-N

General description

3,6,9-Trioxaundecanedioic, acid also known as tetraglycolic acid, is a water miscible hydrophilic cross-linking reagent, widely utilized in PEGylation reactions.

Application

3,6,9-Trioxaundecanedioic acid is used as a cross linking agent in the synthesis of biodegradable, kojic acid-based poly(carbonate-esters).


pictograms

Corrosion

signalword

Danger

hcodes

Hazard Classifications

Eye Dam. 1

Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter



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Biodegradable kojic acid-based polymers: controlled delivery of bioactives for melanogenesis inhibition
JJ Faig
Biomacromolecules, 18, 363-373 (2017)
Jonathan J Faig et al.
Biomacromolecules, 18(2), 363-373 (2016-12-28)
Kojic acid (KA) is a naturally occurring fungal metabolite that is utilized as a skin-lightener and antibrowning agent owing to its potent tyrosinase inhibition activity. While efficacious, KA's inclination to undergo pH-mediated, thermal-, and photodegradation reduces its efficacy, necessitating stabilizing



Global Trade Item Number

SKUGTIN
92893-50ML04061838121271
92893-250ML04061838129741