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Merck
CN

929786

PCL-PEG-PCL diacrylate

PCL average Mn 200, PEG average Mn 1000

Synonym(s):

Biodegradable triblock copolymer, PCL-b-PEG-b-PCL, PEG hydrogel, Polyethylene glycol, acrylate-PCL-PEG-PCL-acrylate

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About This Item

Linear Formula:
C2H3O2(C6H10O2)x(C2H4O)y(OC6H10O)zOC2H3
UNSPSC Code:
12162002
NACRES:
NA.25
eCl@ss:
32150312
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form

low-melting solid

Quality Segment

mol wt

PCL average Mn 200, PEG average Mn 1000

contains

MEHQ as stabilizer

color

white to off-white

Ω-end

acrylate

α-end

acrylate

storage temp.

−20°C

SMILES string

O=C(OCCOC(CCCCCOC(C=C)=O)=O)CCCCCOC(C=C)=O

InChI

1S/C20H30O8/c1-3-17(21)25-13-9-5-7-11-19(23)27-15-16-28-20(24)12-8-6-10-14-26-18(22)4-2/h3-4H,1-2,5-16H2

InChI key

PCLZPCUCIICUMZ-UHFFFAOYSA-N

General description

PCL-PEG-PCL diacrylate, average Mn 100-1000-100, is a functionalized, amphiphilic triblock copolymer composed of a central hydrophilic, biocompatible poly(ethylene glycol) (PEG) block and two terminal hydrophobic, biodegradable poly(caprolactone) (PCL) blocks. PCL-PEG-PCL diacrylate can be crosslinked via free radical polymerization and/or photopolymerization to form a crosslinked hydrogel network. Hydrolysis of the esters of the PCL blocks permits degradation of the crosslinked networks.

Application

  • Tissue engineering
  • 3D printing
  • Drug delivery

Features and Benefits

  • PCL-PEG-PCL triblock copolymer
  • Hydrolytically degradable PCL blocks
  • Acrylate functional groups permit photopolymerization


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Storage Class

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable



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