936618
(S,R,S)-AHPC-CO-PEG4-C2-amine HCl
≥95%
别名:
(2S,4R)-1-((S)-1-amino-17-(tert-butyl)-15-oxo-3,6,9,12-tetraoxa-16-azaoctadecan-18-oyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride, (2S,4R)-1-[(2S)-2-(1-amino-3,6,9,12-tetraoxapentadecan-15-amido)-3,3-dimethylbutanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide hydrochloride
选择规格
关于此项目
Quality Segment
assay
≥95%
form
crystals (or crystals with chunks)
color
White to Light Yellow
storage temp.
2-8°C
SMILES string
C([C@@H](NC(CCOCCOCCOCCOCCN)=O)[C@](C)(C)C)(=O)N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1.Cl
InChI
1S/C33H51N5O8S.ClH/c1-23-29(47-22-36-23)25-7-5-24(6-8-25)20-35-31(41)27-19-26(39)21-38(27)32(42)30(33(2,3)4)37-28(40)9-11-43-13-15-45-17-18-46-16-14-44-12-10-34;/h5-8,22,26-27,30,39H,9-21,34H2,1-4H3,(H,35,41)(H,37,40);1H/t26-,27+,30-;/m1./s1
InChI key
XKGVWUPEGSRRJY-ABLBDAGXSA-N
Application
Technology Spotlight:
Degrader Building Blocks for Targeted Protein Degradation
Protein Degrader Building Blocks
Other Notes
Destruction of DNA-Binding Proteins by Programmable Oligonucleotide PROTAC (O′PROTAC): Effective Targeting of LEF1 and ERG
Small-Molecule PROTACS: New Approaches to Protein Degradation
Targeted Protein Degradation: from Chemical Biology to Drug Discovery
Impact of linker length on the activity of PROTACs
存储类别
11 - Combustible Solids
flash_point_f
Not applicable
flash_point_c
Not applicable