Human skin derived collagen type I

Human skin-derived type I collagen is a natural biomaterial extracted from nutrient-rich skin tissue. As the most abundant type of collagen in the human body, it serves as a major structural matrix protein in skin, as well as in other vital tissues such as bone, tendon, and fibrous connective tissues. Type I collagen is a heterotrimer composed of one α2 chain and two α1 chains, arranged in a triple helical conformation. This unique structure allows various cell surface receptors to recognize and attach to collagen materials. Notably, the integrins α1β1 and α2β1 are among the most characterized receptors that facilitate this attachment.

This versatile scaffolding material is specifically designed for tissue engineering applications, offering a robust and porous structure that supports the growth and regeneration of essential tissues, including skin, cartilage, bone, and blood vessels. It can be reconstituted to a desired concentration to suit a wide range of biomedical research applications. This material is isolated from human tissue sourced strictly from American Association of Tissue Banks (AATB) accredited and FDA registered tissue bands and organ procurement organization (OPOs) and strives to meet research needs by providing high quality biomaterials.

This human skin derived type I collagen solution can be used in a variety of biomedical research applications including:

• Enhancing cell attachment, growth, and tissue production for in vitro modeling applications
• Creating 3D hydrogels for tissue engineering and regenerative medicine Supporting the growth of various cell types including mesenchymal stem cells (MSCs), fibroblasts and endothelial cells
• Servicing as a matrix for wound healing and/or drug delivery systems

Features

• Human-Derived Type I Collagen: Sourced from nutrient-rich skin tissue for high quality and biocompatibility.
• Triple Helical Structure: Facilitates effective cell attachment through recognition by cell surface receptors.
• Versatile Applications: Suitable for coatings, hydrogels, and scaffolds in tissue engineering. Benefits
• Enhanced Cell Adhesion: Promotes rapid cell attachment and growth for improved experimental outcomes.
• Support for Regenerative Medicine: Provides a reliable matrix for developing functional tissues.
• Customizable Solutions: Adjustable collagen concentration allows for tailored applications based on specific needs.

Purchaser shall not make any attempt to trace or identify donors from whom the HBS material was obtained. Purchaser shall use any data (including genetic information), generated with or by use of the HBS only in compliance with obligations of confidentiality and non-use equivalent with all applicable international and national legislation and guidelines on the protection of personal data and confidentiality, such as EU Directive 95/46 and EU Regulation 2016/679. In addition to the use restrictions contained on the product label and/or product datasheet or other applicable use terms and conditions of sale, Purchaser agrees to use the HBS solely in accordance with the World Medical Association (WMA) Declaration of Helsinki, adopted in 1964 as subsequently amended by WMA on Ethical Principles for Medical Research Involving Human Subjects.