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Merck
CN

94295

3-Ureidopropionic acid

≥98.0% (T)

Synonym(s):

N-Carbamoyl-β-alanine

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About This Item

Linear Formula:
NH2CONHCH2CH2COOH
CAS Number:
Molecular Weight:
132.12
UNSPSC Code:
12352106
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
1705263
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InChI

1S/C4H8N2O3/c5-4(9)6-2-1-3(7)8/h1-2H2,(H,7,8)(H3,5,6,9)

SMILES string

NC(=O)NCCC(O)=O

InChI key

JSJWCHRYRHKBBW-UHFFFAOYSA-N

assay

≥98.0% (T)

form

powder

reaction suitability

reaction type: solution phase peptide synthesis

mp

170-175 °C (dec.)

application(s)

peptide synthesis

Quality Level

Storage Class

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Improved colorimetric procedure for quantitating N-carbamoyl-beta-alanine with minimum dihydrouracil interference.
T P West et al.
Analytical biochemistry, 122(2), 345-347 (1982-05-15)
G Waldmann et al.
Analytical biochemistry, 188(1), 233-236 (1990-07-01)
A sensitive assay for beta-ureidopropionase based on derivatization of the reaction product beta-alanine with phenylisothiocyanate has been developed. Purification of the resulting phenylthiocarbamoyl-beta-alanine is achieved on a LiChrospher 100 C18 reversed-phase high-performance liquid chromatography column using an isocratic elution system.
C Schmidt et al.
Journal of inherited metabolic disease, 28(6), 1109-1122 (2006-01-26)
To evaluate the significance of inborn metabolic disorders of the pyrimidine degradation pathway, 450 children with unspecific neurological symptoms were comprehensively studied; 200 healthy children were recruited as controls. Uracil and thymine as well as their degradation products in urine
Simple method for the quantitative analysis of dihydropyrimidines and N-carbamyl-beta-amino acids in urine.
A H van Gennip et al.
Advances in experimental medicine and biology, 309B, 15-19 (1991-01-01)
B Zarabian et al.
Analytical biochemistry, 166(1), 113-119 (1987-10-01)
Two modified procedures for the colorimetric quantitation of citrulline aimed primarily at the assay of ornithine transcarbamylase were developed. Both methods give highly reproducible results in a short period of time since color is developed in 25 min at 100

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