944211
Poly(D,L-lactic-co-glycolic acid)-block-poly(glutamic acid)
PLGA average Mn 40,000, mol wt (PGlu average Mn 2,000), lactide:glycolide 50:50
Synonym(s):
Amphiphilic block copolymer, Glutamic acid, Lactic-co-glycolic acid-based polymer, PLGA, PLGA-b-PGA, PLGA-b-PGlu, Poly(DL-lactide-co-glycolide)-block-poly(glutamic acid), Poly(glutamic acid) block polymer, Polyaminoacids
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form
powder
Quality Segment
feed ratio
lactide:glycolide 50:50
mol wt
PLGA average Mn 40,000, (PGlu average Mn 2,000)
color
white to beige
shipped in
dry ice
storage temp.
−20°C
General description
PLGA-b-PGA block copolymer is a innovative material engineered to accelarate drug delivery and biomedical research. This amphiphilic copolymer combines the hydrophobic, biodegradable properties of PLGA with the hydrophilic, biocompatible nature of poly(glutamic acid) (PGA), offering unmatched versatility for tailored therapeutic applications.
Application
This polymer is a amphiphilic diblock copolymer composed of a hydrophobic PLGA block and a hydrophilic poly(glutamic acid) block. PLGA is a biocompatible and biodegradable polymer that has been approved by the FDA and the EMA for biomedical and pharmaceutical applications. Poly(glutamic acid) is biodegradable, non-toxic and non-immunogenic macromolecules. This biodegradable, biocompatible polymer can self-assemble to form nanoparticles, such as micelles and polymersomes, for controlled release of molecules applications
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Storage Class
11 - Combustible Solids
Flash Point (°F)
Not applicable
Flash Point (°C)
Not applicable
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