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Merck
CN

96085

Z-Dap-OH

≥98.0% (NT)

Synonym(s):

Nα-Z-L-2,3-Diaminopropionic acid, Z-Dpr-OH

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About This Item

Linear Formula:
H2NCH2CH(NHCO2CH2C6H5)CO2H
CAS Number:
Molecular Weight:
238.24
UNSPSC Code:
12352200
NACRES:
NA.22
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
4486950
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assay

≥98.0% (NT)

form

crystals

optical activity

[α]20/D −39±1°, c = 1% in 1 M HCl

reaction suitability

reaction type: solution phase peptide synthesis

mp

~240 °C (dec.)

application(s)

peptide synthesis

SMILES string

NC[C@H](NC(=O)OCc1ccccc1)C(O)=O

InChI

1S/C11H14N2O4/c12-6-9(10(14)15)13-11(16)17-7-8-4-2-1-3-5-8/h1-5,9H,6-7,12H2,(H,13,16)(H,14,15)/t9-/m0/s1

InChI key

FOXRXVSTFGNURG-VIFPVBQESA-N

Other Notes

Important building block for the synthesis of peptides containing DAP residues, e.g. bleomycins, edeines, tuberactinomycins


Storage Class

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Regulatory Information

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C. Mendre et al.
Tetrahedron Letters, 35, 5429-5429 (1994)
Y. Funabashi et al.
Tetrahedron, 49, 13-13 (1993)
S Shinagawa et al.
Journal of medicinal chemistry, 30(8), 1458-1463 (1987-08-01)
Emericedins A, B, and C, new betaines having inhibitory activity of long chain fatty acid oxidation, were isolated from the culture broth of Emericella quadrilineata IFO 5859. Their structures were determined by spectroscopic analyses as (R)-3-(acylamino)-4-(trimethylammonio)butyrate (acyl: A, acetyl; B



Global Trade Item Number

SKUGTIN
96085-5G04061832596839