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A10507

Acetone oxime

Name: Acetone oxime
Brand: ALDRICH

98%

Synonym(s):

β-Isonitrosopropane, 2-Propanone oxime, Acetoxime, Dimethyl ketoxime, N-Isopropylidenehydroxylamine, Propanone oxime

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About This Item

Linear Formula:

(CH₃)₂C=NOH

CAS Number:

127-06-0

Molecular Weight:

73.09

UNSPSC Code:

12352100

NACRES:

NA.02

PubChem Substance ID:

24890499

EC Number:

204-820-1

Beilstein/REAXYS Number:

1560146

MDL number:

MFCD00002118

Assay:

98%

Form:

crystals

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Properties

assay

98%

form

crystals

bp

135 °C (lit.)

mp

60-63 °C (lit.)

density

0.901 g/mL at 25 °C (lit.)

SMILES string

C\C(C)=N/O

InChI

1S/C3H7NO/c1-3(2)4-5/h5H,1-2H3

InChI key

PXAJQJMDEXJWFB-UHFFFAOYSA-N

Description

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pictograms

GHS02,GHS08,GHS05,GHS07

signalword

Danger

hcodes

H228,H312,H317,H318,H351

pcodes

P202 - P210 - P280 - P302 + P352 + P312 - P305 + P351 + P338 - P308 + P313

Hazard Classifications

Acute Tox. 4 Dermal - Carc. 2 - Eye Dam. 1 - Flam. Sol. 2 - Skin Sens. 1B

Storage Class

4.1B - Flammable solid hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Sex and organ differences in oxidative DNA and RNA damage due to treatment of Sprague-Dawley rats with acetoxime or 2-nitropropane.

N Guo et al.

Carcinogenesis, 11(9), 1659-1662 (1990-09-01)

The hepatocarcinogens 2-nitropropane and acetoxime have previously been found to induce a specific and qualitatively identical pattern of base damage in rat liver DNA and RNA, including the induction of increased levels of 8-hydroxyguanine. Because both 2-nitropropane and acetoxime are

Induction of hyperplastic liver nodules in Wistar and MRC-Wistar rats by phenobarbital and the liver carcinogens acetoxime, 1-nitroso-5,6-dihydrouracil and 3-nitroso-2-oxazolidinone.

S S Mirvish et al.

Cancer letters, 41(2), 211-216 (1988-08-15)

We tested the ability of phenobarbital and two liver carcinogens, acetoxime and 1-nitroso-5,6-dihydrouracil (NDHU), to induce hyperplastic liver nodules (HLN) in MRC-Wistar and Wistar rats, using a system that included a single diethylnitrosamine (DEN) treatment, partial hepatectomy, and administration of

Genotoxicity of N-nitroso-N-methylurea and acetone oxime in the transgenic Drosophila carrying the human gene encoding a subunit of glutathione S-transferase.

M Rysková et al.

Folia biologica, 43(1), 19-24 (1997-01-01)

The genotoxic effects of N-nitroso-N-methylurea (MNU) and acetone oxime (ACOX) were tested in the Somatic Mutation and Recombination Test (SMART) in Drosophila melanogaster. We have performed the same assay on transgenic flies expressing the human gene encoding a glutathione S-transferase

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Global Trade Item Number

SKU	GTIN
A10507-100G	04061832102979