A48407
4-Amino-2,6-dichlorophenol
98%
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About This Item
Linear Formula:
H2NC6H2(Cl)2OH
CAS Number:
Molecular Weight:
178.02
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
EC Number:
227-671-4
MDL number:
Assay:
98%
Form:
powder
Product Name
4-Amino-2,6-dichlorophenol, 98%
InChI
1S/C6H5Cl2NO/c7-4-1-3(9)2-5(8)6(4)10/h1-2,10H,9H2
InChI key
KGEXISHTCZHGFT-UHFFFAOYSA-N
SMILES string
Nc1cc(Cl)c(O)c(Cl)c1
assay
98%
form
powder
mp
167-170 °C (lit.)
Quality Level
Related Categories
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2
Storage Class
11 - Combustible Solids
wgk
WGK 3
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Benoît Limoges et al.
Journal of the American Chemical Society, 130(23), 7276-7285 (2008-05-22)
The two articles in this series are dedicated to bioaffinity electrodes with in situ detection of the product of the enzyme label after recognition by its conjugate immobilized on the electrode. Part 1 was devoted to direct electrochemical detection, whereas
Gary O Rankin et al.
Toxicology, 245(1-2), 123-129 (2008-02-05)
4-Amino-2,6-dichlorophenol (ADCP) is a potent acute nephrotoxicant in vivo inducing prominent renal corticomedullary necrosis. In vitro, ADCP exposure increases lactate dehydrogenase (LDH) release from rat renal cortical slices at 0.05 mM or greater. The purpose of this study was to
G O Rankin et al.
Toxicology, 90(1-2), 115-128 (1994-05-31)
Halogenated anilines and aminophenols are nephrotoxicants and hepatotoxicants in mammals. The purpose of this study was to determine the in vivo and in vitro nephrotoxic and hepatotoxic potential of 4-amino-2,6-dichlorophenol, a putative metabolite of 3,5-dichloroaniline. In the in vivo experiments
S K Hong et al.
Toxicology and applied pharmacology, 147(1), 115-125 (1997-11-14)
A halogenated derivative of 4-aminophenol, 4-amino-2, 6-dichlorophenol (ADCP), is a potent nephrotoxicant and a weak hepatotoxicant in Fischer 344 rats. Although the mechanism of ADCP nephrotoxicity is unknown, ADCP could undergo oxidation to a reactive intermediate, such as a 4-amino-2,6-dichlorophenoxy
Benoît Limoges et al.
Journal of the American Chemical Society, 130(23), 7259-7275 (2008-05-21)
The use of enzyme labeling techniques to convert biorecognition events into high sensitivity electrochemical signals may follow two different strategies. One, in which the current is the electrocatalytic response of a redox couple serving as cosubstrate to a redox enzyme
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