A55004
4-(2-Aminoethyl)morpholine
99%
Synonym(s):
2-Morpholinoethylamine
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About This Item
Empirical Formula (Hill Notation):
C6H14N2O
CAS Number:
Molecular Weight:
130.19
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
EC Number:
218-011-6
Beilstein/REAXYS Number:
104378
MDL number:
Assay:
99%
Form:
solid
InChI key
RWIVICVCHVMHMU-UHFFFAOYSA-N
InChI
1S/C6H14N2O/c7-1-2-8-3-5-9-6-4-8/h1-7H2
SMILES string
NCCN1CCOCC1
assay
99%
form
solid
Quality Level
bp
205 °C (lit.)
density
0.992 g/mL at 25 °C (lit.)
Related Categories
Application
4-(2-Aminoethyl)morpholine is widely used in biomedical applications as this moiety serves as an important lysosome-targeting group. Some of its applications include:
- Synthesis of the lysosome-targetable fluorescent probe for hydrogen sulfide imaging in living cells.
- Synthesis of 1,8-naphthalimide conjugated Troger′s bases as deoxyribonucleic acid (DNA) targeting fluorescent probe.
- Synthesis of intramolecular charge transfer-photoinduced electron transfer-fluorescence resonance energy transfer (ICT-PET-FRET) fluorescent probe for monitoring pH changes in living cells.
- It is also used as a precursor to synthesize a variety of antimicrobial agents.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Skin Corr. 1B - Skin Sens. 1
Storage Class
8A - Combustible corrosive hazardous materials
wgk
WGK 2
flash_point_f
186.8 °F - closed cup
flash_point_c
86 °C - closed cup
ppe
Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges
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A lysosome-targetable fluorescent probe for imaging hydrogen sulfide in living cells.
Liu T, et al.
Organic Letters, 15(9), 2310-2313 (2013)
Małgorzata Góra et al.
International journal of molecular sciences, 21(16) (2020-08-17)
The present study aimed to design and synthesize a new series of hybrid compounds with pyrrolidine-2,5-dione and thiophene rings in the structure as potential anticonvulsant and antinociceptive agents. For this purpose, we obtained a series of new compounds and evaluated
Danford Mhule et al.
International journal of pharmaceutics, 550(1-2), 149-159 (2018-08-21)
Stimuli-responsive nano-drug delivery systems can optimize antibiotic delivery to infection sites. Identifying novel lipids for pH responsive delivery to acidic conditions of infection sites will enhance the performance of nano-drug delivery systems. The aim of the present investigation was to
Dual site-controlled and lysosome-targeted intramolecular charge transfer?photoinduced electron transfer?fluorescence resonance energy transfer fluorescent probe for monitoring pH changes in living cells.
Dong B, et al.
Analytical Chemistry, 88(7), 4085-4091 (2016)
Arup Podder et al.
Journal of photochemistry and photobiology. B, Biology, 177, 105-111 (2017-11-08)
A self-calibrated fluorescent probe Lyso-Phos has synthesized followed by a straightforward synthetic pathway. Lyso-Phos acts as an indicator for lysosomal phosphatase. Its photophysical property including cellular imaging was described. Lyso-Phos showed ratiometric UV-Vis- absorption changes from λ
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