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Merck
CN

A65158

4-(Aminomethyl)piperidine

greener alternative

96%

Synonym(s):

4-AMP, 4-Piperidinemethanamine

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About This Item

Empirical Formula (Hill Notation):
C6H14N2
CAS Number:
7144-05-0
Molecular Weight:
114.19
UNSPSC Code:
12352100
NACRES:
NA.22
PubChem Substance ID:
24891098
EC Number:
230-446-3
Beilstein/REAXYS Number:
471185
MDL number:
MFCD00006007
Assay:
96%
Form:
solid

Key Documents

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InChI key

LTEKQAPRXFBRNN-UHFFFAOYSA-N

InChI

1S/C6H14N2/c7-5-6-1-3-8-4-2-6/h6,8H,1-5,7H2

SMILES string

NCC1CCNCC1

assay

96%

form

solid

greener alternative product characteristics

Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

refractive index

n20/D 1.49 (lit.)

bp

200 °C (lit.)

mp

25 °C (lit.)

greener alternative category

Enabling,

Quality Level

100

Related Categories

General description

We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for energy efficiency. Find details here.

Application

4-(Aminomethyl)piperidine (4-AMP) can be used in the synthesis of Schiff bases. It is a trifunctional amine for the preparation of linear poly(amido amine)s, which form micelles for controlled delivery of drugs. 4-AMP can also be used as a linker for the synthesis of dendron-OMS hybrids.
Reactant:
  • Evaulated as a small molecule inhibitor of CD4-gp120 binding

Reagent
  • Involved in solvothermal preparation of germanium oxide hydroxide 3D net zeotype
  • Involved in zeolite synthesis

Coupling agent for adhesive systems

signalword

Danger

pictograms

Corrosion
GHS05

hcodes

H314

Hazard Classifications

Eye Dam. 1 - Skin Corr. 1B

Storage Class

8A - Combustible corrosive hazardous materials

wgk

WGK 3

flash_point_f

172.4 °F - closed cup

flash_point_c

78 °C - closed cup

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificates of Analysis (COA)

Lot/Batch Number
0000263996
0000263996
0000201378
0000201379
0000167529

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Catalytic properties of dendron-OMS hybrids
Wang Q, et al.
J. Catal., 269(1), 15-25 (2010)
Synthesis, characterization, antimicrobial activity, and optical properties of Schiff bases derived from 4-(Aminomethyl) Piperidine
Karthik CS, et al.
Indian Journal of Advances in Chemical Science, 206, 212-212 (2016)
p H-and Redox-R esponsive Poly (ethylene glycol) and Cholesterol-C onjugated Poly (amido amine) s Based Micelles for Controlled Drug Delivery
Cheng W, et al.
Macromolecular Bioscience, 14(3), 347-358 (2014)
Lingling Mao et al.
Journal of the American Chemical Society, 140(10), 3775-3783 (2018-02-22)
The three-dimensional hybrid organic-inorganic perovskites have shown huge potential for use in solar cells and other optoelectronic devices. Although these materials are under intense investigation, derivative materials with lower dimensionality are emerging, offering higher tunability of physical properties and new

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