A79922
9-Amino-1,2,3,4-tetrahydroacridine hydrochloride hydrate
≥99%
Synonym(s):
THA hydrochloride hydrate, Tacrine hydrochloride, Tetrahydroaminacrine hydrochloride hydrate
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About This Item
Empirical Formula (Hill Notation):
C13H14N2 · HCl · xH2O
CAS Number:
Molecular Weight:
234.72 (anhydrous basis)
NACRES:
NA.22
PubChem Substance ID:
UNSPSC Code:
12352100
MDL number:
Assay:
≥99%
Form:
solid
Quality Level
assay
≥99%
form
solid
mp
284-286 °C (lit.)
SMILES string
O.Cl.Nc1c2CCCCc2nc3ccccc13
InChI
1S/C13H14N2.ClH.H2O/c14-13-9-5-1-3-7-11(9)15-12-8-4-2-6-10(12)13;;/h1,3,5,7H,2,4,6,8H2,(H2,14,15);1H;1H2
InChI key
PXGRMZYJAOQPNZ-UHFFFAOYSA-N
Application
9-Amino-1,2,3,4-tetrahydroacridine hydrochloride hydrate is a well-known cholinesterase inhibitor commonly used in pharmacological studies.
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signalword
Danger
Hazard Classifications
Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Storage Class
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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The ameliorating effects of stigmasterol on scopolamine-induced memory impairments in mice.
Park SJ, et al.
European Journal of Pharmacology, 676(1-3), 64-70 (2012)
Acetylcholinesterase capillary enzyme reactor for screening and characterization of selective inhibitors.
da Silva JI, et al.
Journal of Pharmaceutical and Biomedical Analysis, 73, 44-52 (2013)
Comparison of inhibitory activities of donepezil and other cholinesterase inhibitors on acetylcholinesterase and butyrylcholinesterase in vitro.
Ogura H, et al.
Methods and Findings in Experimental and Clinical Pharmacology, 22(8), 609-614 (2000)
Global Trade Item Number
| SKU | GTIN |
|---|---|
| A79922-5G | 04061833390924 |
| A79922-1G | 04061833390917 |