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A88182

Sigma-Aldrich

o-Anisidine

≥99%

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Synonym(s):
2-Aminoanisole, 2-Methoxyaniline
Linear Formula:
CH3OC6H4NH2
CAS Number:
90-04-0
Molecular Weight:
123.15
Beilstein:
386210
EC Number:
201-963-1
MDL number:
MFCD00007688
PubChem Substance ID:
24891370
NACRES:
NA.22

Quality Level

200

Assay

≥99%

form

liquid

refractive index

n20/D 1.574 (lit.)

bp

225 °C (lit.)

mp

3-6 °C (lit.)

density

1.092 g/mL at 25 °C (lit.)

SMILES string

COc1ccccc1N

InChI

1S/C7H9NO/c1-9-7-5-3-2-4-6(7)8/h2-5H,8H2,1H3

InChI key

VMPITZXILSNTON-UHFFFAOYSA-N

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General description

o-Anisidine is an aromatic amine used as a building block for the production of dyes, pigments, and pharmaceuticals.

Pictograms

Skull and crossbonesHealth hazard
GHS06,GHS08

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Carc. 1B - Muta. 2

Storage Class Code

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Flash Point(F)

212.0 °F - closed cup

Flash Point(C)

100 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Regulatory Information

危险化学品

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D Sangamithirai et al.
Materials science & engineering. C, Materials for biological applications, 91, 512-523 (2018-07-24)
Dopamine (DA) and Folic acid (FA) are co-existing compounds in biological fluids that plays a vital role in central nervous system and human metabolism. DA is an important neurotransmitter in the brain's neural circuits and its diminution often results in
Parimal Routh et al.
Biophysical chemistry, 143(3), 145-153 (2009-06-02)
Biomolecular hybrids of a conducting polymer [poly(o-methoxy aniline) (POMA)] and RNA are prepared at the three different compositions by mixing aqueous solutions of diethyl, 2-hydroxy ethyl, ammonium salt of RNA (type IX from Torula Yeast) and POMA (ES, emeraldine salt;
Paulo A Ribeiro et al.
Journal of nanoscience and nanotechnology, 6(5), 1396-1404 (2006-06-24)
Neutron reflectivity measurements were used to investigate the thermal stability of layer-by-layer (LBL) films of poly(o-methoxyaniline) (POMA), which was probed by increasing the temperature up to 80 degrees C of a D2O solution in contact with the LBL films. The
Marie Stiborová et al.
Mutation research, 500(1-2), 49-66 (2002-03-14)
2-Methoxyaniline (o-anisidine) is a urinary bladder carcinogen in both mice and rats. Since the urinary bladder contains substantial peroxidase activity, we investigated the metabolism of this carcinogen by prostaglandin H synthase (PHS), a prominent enzyme in the urinary bladder, and
Karel Naiman et al.
Toxicological sciences : an official journal of the Society of Toxicology, 127(2), 348-359 (2012-03-10)
2-Methoxyaniline (o-anisidine) is an industrial and environmental pollutant causing tumors of urinary bladder in rodents. Here, we investigated the formation and persistence of DNA adducts in the Wistar rat. Using the (32)P-postlabeling method, three o-anisidine-derived DNA adducts were found in
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